Evidence map›Paper›PMID 40590824›Full record

Observational studyAnnals of emergency medicine2026

Does Exposure to Certified Stroke Centers Affect All Communities Equitably? Stroke Patient Outcomes by Community Socioeconomic Status.

Yu-Chu Shen, Anthony S Kim, Renee Y Hsia

Abstract readObservational Study
In one paragraph

Observational study in Annals of emergency medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Yu-Chu ShenDepartment of Defense Management, Naval Postgraduate School, Monterey, CA; National Bureau of Economic Research, Cambridge, MA.
Anthony S KimWeill Institute of Neurosciences, Department of Neurology, University of California, San Francisco, CA.
Renee Y HsiaDepartment of Emergency Medicine, University of California, San Francisco, CA; Philip R. Lee Institute for Health Policy Studies, University of California, San Francisco, CA. Electronic address: renee.hsia@ucsf.edu.

Funding

NBER Center for Aging and Health Research-Post COVID-19 Experiences Among Adults with ADRDP30AG012810 · NIA · NATIONAL BUREAU OF ECONOMIC RESEARCH · PI DAVID M CUTLER, Karen Ellen Joynt Maddox · 1999 to 2026
$24.6M
Structural Racism and Discrimination in the Expansion of Hospital Stroke Care Capacity: A Multi-Level Analysis on Access to Care, Treatment, and OutcomesR01MD017482 · NIMHD · NATIONAL BUREAU OF ECONOMIC RESEARCH · PI HSIA, RENEE YUEN-JAN, SHEN, YU-CHU · 2022 to 2025
$2.2M
NIA NIH HHS P30 AG012810NIMHD NIH HHS R01 MD017482
6 · The paper itself

Abstract

STUDY

objectiveTo determine how access, treatment, and outcomes change for patients after their community is exposed to a newly certified stroke center based on a community's disadvantage status.

methodsIn this retrospective observational study, we included Medicare Fee-for-Service patients from a national claims-based database admitted to hospitals between January 2009 and December 2019 whose primary diagnosis was acute ischemic stroke. We implemented linear probability models with community fixed effects to compare changes in outcomes when communities were exposed to newly certified stroke centers nearby relative to similar communities that did not experience stroke center expansion, controlling for patient demographics and comorbid conditions and secular trends. Outcomes included admission to a certified stroke center, receipt of thrombolytic therapy or mechanical thrombectomy, and 1-year mortality.

resultsWe analyzed 2,807,763 patients with acute ischemic stroke. Only 68% of those in disadvantaged communities had exposure to a newly certified stroke center nearby during the study period, whereas 92% of those in advantaged communities had the same exposure. In disadvantaged communities, new stroke centers were associated with a 23.1 percentage point (pp) increase in admission to a stroke center, a 0.3 pp increase in "drip-and-ship" thrombolytic therapy, a 0.2 pp decrease in thrombectomy, and no statistically significant changes in "drip-and-stay" thrombolytic therapy or 1-year mortality. In advantaged communities, new stroke centers were associated with a 4.2 pp increase in admission to a stroke center, a 0.6 pp decrease in "drip-and-ship" thrombolytic therapy, a 0.8 pp increase in "drip-and-stay" thrombolytic therapy, a 0.2 pp increase in thrombectomy, and a small reduction in 1-year mortality of 0.6 pp.

conclusionStroke center expansion has been uneven, and its effects on patient care differ by a community's socioeconomic status. These findings should guide stroke center initiatives to improve care in disadvantaged communities.

Indexed as

Healthcare DisparitiesHealth Services AccessibilityIschemic StrokeSocial ClassStrokeAgedAged, 80 and overFemaleHumansMaleMedicareRetrospective StudiesThrombectomyThrombolytic TherapyUnited StatesAcute ischemicCertificationStrokeTreatment outcome

Identifiers

PMID40590824
PMCPMC12323391

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.