Evidence map›Paper›PMID 40590667›Full record

ArticleAngewandte Chemie (International ed. in English)2025

Expanding the Inositol Pyrophosphate Toolbox: Stereoselective Synthesis and Application of PP-InsP

Kevin Ritter, Anne-Sophie C Braun, Guizhen Liu, Mengsi Lu, Verena Gaugler, Gabriel Schaaf, Henning Jacob Jessen

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Angewandte Chemie (International ed. in English), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Review
  3. Affinity-Based Interactome Mapping of Inositol Pyrophosphates Reveals 4/6-PP-InsPAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  4. Article
  5. EstablishingAnalytical chemistry · 2025
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Kevin RitterFaculty of Chemistry and Pharmacy, Institute of Organic Chemistry, and CIBSS-Centre for Integrative Biological Signaling Studies, Albert-Ludwigs University Freiburg, Freiburg, 79104, Germany.
Anne-Sophie C BraunFaculty of Chemistry and Pharmacy, Institute of Organic Chemistry, and CIBSS-Centre for Integrative Biological Signaling Studies, Albert-Ludwigs University Freiburg, Freiburg, 79104, Germany.
Guizhen LiuFaculty of Chemistry and Pharmacy, Institute of Organic Chemistry, and CIBSS-Centre for Integrative Biological Signaling Studies, Albert-Ludwigs University Freiburg, Freiburg, 79104, Germany.
Mengsi LuFaculty of Chemistry and Pharmacy, Institute of Organic Chemistry, and CIBSS-Centre for Integrative Biological Signaling Studies, Albert-Ludwigs University Freiburg, Freiburg, 79104, Germany.
Verena GauglerDepartment of Plant Nutrition, Institute of Crop Science and Resource Conservation, Rheinische Friedrich-Wilhelms-Universität Bonn, Bonn, 53115, Germany.
Gabriel SchaafDepartment of Plant Nutrition, Institute of Crop Science and Resource Conservation, Rheinische Friedrich-Wilhelms-Universität Bonn, Bonn, 53115, Germany.ORCID 0000-0001-9022-4515
Henning Jacob JessenFaculty of Chemistry and Pharmacy, Institute of Organic Chemistry, and CIBSS-Centre for Integrative Biological Signaling Studies, Albert-Ludwigs University Freiburg, Freiburg, 79104, Germany.ORCID 0000-0002-1025-9484

Funding

Deutsche Forschungsgemeinschaft CIBSSDeutsche Forschungsgemeinschaft EXC-2189Deutsche Forschungsgemeinschaft Project ID 390939984Deutsche Forschungsgemeinschaft SCHA 1274/5-1Volkswagen Foundation VW Momentum Grant 98604
6 · The paper itself

Abstract

Inositol pyrophosphates (PP-InsPs) are highly phosphorylated signaling molecules that regulate diverse cellular processes, including phosphate homeostasis and energy metabolism across species. Despite extensive research on well-characterized exhaustively phosphorylated PP-InsPs, such as 5-PP-InsP

Indexed as

ArabidopsisInositol PhosphatesIsomerismPhosphorylationSignal TransductionStereoisomerismInositol PhosphatesCapillary electrophoresis mass spectrometryInositol phosphatesInositol pyrophosphatesPhosphate homeostasisPhosphorylation

Identifiers

PMID40590667
PMCPMC12402868

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.