ArticleInternational journal of fertility & sterility2025
The Relation between Celiac Disease and Ovarian Reserve: A Case-Control Study.
Article in International journal of fertility & sterility, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed, 1 synthesis or guideline pooled it.
- Association of celiac disease with menstrual and hormonal disturbances: a systematic review and meta-analysis.Reproductive biology and endocrinology : RB&E · 2026Pooled it
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCeliac disease (CD) is one of the most prevalent chronic digestive disorders, often presenting with intestinal symptoms as well beyond. These symptoms may include reproductive complications. To gain a deeper understanding of a women's fertility potential, medical professionals employ sonographic and laboratory techniques to predict the ovarian reserve. The aim of this study was to explore the ovarian reserve in women affected by CD in comparison to healthy women in their reproductive years, this study aimed to find the relationship between CD and ovarian reserve. MATERIALS AND
methodsThis case-control study included a total of 27 patients diagnosed with CD, alongside an agematched group of 27 women without CD. A comprehensive checklist for demographic information was completed for each participant. During days 2-4 of the menstrual cycle, blood samples were collected to measure the levels of follicular stimulating hormones (FSH), luteinizing hormone (LH), thyroid stimulating hormone (TSH), anti-mullerin hormone (AMH), and prolactin. Simultaneously, pelvic ultrasound was conducted to assess the number of antral follicles count (AFC) and ovarian volume on the same day.
resultsThere was no significant difference in age, pregnancy history, spontaneous abortion, stillbirth, premature births, and low birth weight babies between the case and control groups (P>0.05). However, there were significant variations in mean weight, body mass index, and menarche age between the two groups (P<0.05). Moreover, the serum levels of FSH and AFC of the right and left ovaries also showed significant differences between the two groups (P<0.05). However, no significant difference was observed regarding AMH, LH, TSH, prolactin, and ovarian volumes (P>0.05).
conclusionThe present study showed that women with CD have significantly higher AFC and serum FSH levels than healthy women.
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