Trial reportJournal of cosmetic dermatology2025
Effect and Safety of Skincare Regimens Containing a Multi-Molecular Hyaluronic Acid Complex for Recovery After Ablative Fractional CO
Trial report in Journal of cosmetic dermatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Laser treatment of acne scars: a bibliometric analysis and descriptive summary of clinical evidence directions over the past 20 years.Frontiers in medicine · 2026Pooled it
- Effect and Safety of Skincare Regimens Containing a Multi-Molecular Hyaluronic Acid Complex for Recovery After Ablative Fractional COJournal of cosmetic dermatology · 2025Trial
- Retrospective analysis of the clinical efficacy of topical hyaluronic acid in promoting skin recovery and reducing inflammatory reactions after fractional laser treatment.Frontiers in medicine · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
backgroundFractional CO
objectivesThis study evaluates the effect of hyaluronic acid (HA) dressings with different molecular weights (large: medium: low = 2:2:1) on skin barrier repair after CO
methodsIn this prospective, randomized, open-label, controlled trial, patients aged 19-45 who underwent CO
resultsA total of 60 patients were included. On day 14, the TEWL in Group A was significantly lower than in Group B (16.69 vs. 19.79, p = 0.009), and the percentage change in TEWL during the period of the most significant reduction was also greater in Group A than in Group B (-75.10% vs. -70.89%, p = 0.042). The EI in Group A were significantly lower than those in Group B on days 3, 7, and 14 (325.41 vs. 370.83, p = 0.038; 297.77 vs. 338.32, p = 0.041; 287.14 vs. 337.38, p = 0.004). The pain duration in Group A was also significantly shorter than in Group B (0.20 vs. 0.53, p = 0.014). In addition, Group A patients reported higher satisfaction scores on the post-treatment questionnaires.
conclusionsThis study highlights hyaluronic acid with varied molecular sizes enhances post-laser recovery by reducing TEWL and erythema, alleviating pain, and promoting healing.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.