Evidence map›Paper›PMID 40590010›Full record

ArticleTransplantation direct2025

Impact of the Composite Allocation Score on Lung Transplant Waitlist and Posttransplant Outcomes.

Ye In Christopher Kwon, Holly Caboti-Jones, Michael Keller, Andrew Min-Gi Park, Alan Lai, Rachit D Shah, Zachary Fitch, Vigneshwar Kasirajan, Vipul Patel, Zubair A Hashmi

Abstract read
In one paragraph

Article in Transplantation direct, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Impact of preoperative venovenous extracorporeal membrane oxygenation bridging on postoperative acute kidney injury after lung transplantation.Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs · 2026
    Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ye In Christopher KwonDivision of Cardiothoracic Surgery, Department of Surgery, Virginia Commonwealth University School of Medicine, Richmond, VA.ORCID https://orcid.org/0009-0001-4556-1931
Holly Caboti-JonesDivision of Cardiothoracic Surgery, Department of Surgery, Virginia Commonwealth University School of Medicine, Richmond, VA.
Michael KellerDivision of Cardiothoracic Surgery, Department of Surgery, Virginia Commonwealth University School of Medicine, Richmond, VA.
Andrew Min-Gi ParkDivision of Cardiothoracic Surgery, Department of Surgery, Virginia Commonwealth University School of Medicine, Richmond, VA.
Alan LaiDivision of Cardiothoracic Surgery, Department of Surgery, Virginia Commonwealth University School of Medicine, Richmond, VA.
Rachit D ShahDivision of Cardiothoracic Surgery, Department of Surgery, Virginia Commonwealth University School of Medicine, Richmond, VA.
Zachary FitchDivision of Cardiothoracic Surgery, Department of Surgery, Virginia Commonwealth University School of Medicine, Richmond, VA.
Vigneshwar KasirajanDivision of Cardiothoracic Surgery, Department of Surgery, Virginia Commonwealth University School of Medicine, Richmond, VA.
Vipul PatelDivision of Pulmonary Disease and Critical Care Medicine, Department of Internal Medicine, Virginia Commonwealth University School of Medicine, Richmond, VA.
Zubair A HashmiDivision of Cardiothoracic Surgery, Department of Surgery, Virginia Commonwealth University School of Medicine, Richmond, VA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: On March 9, 2023, the Composite Allocation Score (CAS) was introduced for all lung transplantation (LT) candidates. We analyzed waitlist and posttransplant outcomes after CAS implementation. Methods: Using the United Network for Organ Sharing registry (2022-2024), adult patients listed for isolated LT were divided into 2 eras: era 1 (pre-CAS: March 1, 2022-March 8, 2023) and era 2 (post-CAS: March 9, 2023-September 30, 2024). Competing risk regression analyzed waitlist events. Recipient/donor characteristics and mortality risk factors were assessed with Cox models. Survival was evaluated with Kaplan-Meier analysis. Results: Among 6398 LTs, 2598 (40.6%) occurred in era 2. More Black patients (16.9% versus 15%, Conclusions: The implementation of CAS was associated with reduced waitlist mortality, improved access for marginalized groups, and enhanced survival. Lungs were procured from greater distances with an increased use of donation after circulatory death with normothermic regional perfusion or ex vivo perfusion. Disparities remain for ABO type O patients, warranting closer follow-up.

Identifiers

PMID40590010
PMCPMC12208640

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.