Evidence map›Paper›PMID 40589792›Full record

ArticleTransportation research. Part F, Traffic psychology and behaviour2023

Differential Impacts of Road Diets on Driving Behavior among Older Adults with and without Preclinical Alzheimer's Pathology.

Julie K Wisch, Jalil Kianfar, David B Carr, Anne D Dickerson, Jonathon Vivoda, Annie Harmon, Jean Francois Trani, Ann M Johnson, Jason M Doherty, Samantha A Murphy and 8 more

Abstract read
In one paragraph

Article in Transportation research. Part F, Traffic psychology and behaviour, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Julie K WischDepartment of Neurology, Washington University in St. Louis, St. Louis, MO 63110, USA.
Jalil KianfarDepartment of Civil Engineering, St. Louis University, St. Louis, MO 63110 USA.
David B CarrDepartment of Neurology, Washington University in St. Louis, St. Louis, MO 63110, USA.
Anne D DickersonDepartment of Occupational Therapy, East Carolina University, Greenville, NC 27858 USA.
Jonathon VivodaDepartment of Sociology and Gerontology, Miami University, Oxford, OH 45056 USA.
Annie HarmonDepartment of Medicine, Geriatrics and Nutritional Science, Washington University in St. Louis, St. Louis, MO 63110, USA.
Jean Francois TraniBrown School of Social Work, Washington University in St. Louis, St. Louis, MO 63110 USA.
Ann M JohnsonCenter for Clinical Studies, Washington University in St. Louis, St. Louis, MO 63110, USA.
Jason M DohertyDepartment of Neurology, Washington University in St. Louis, St. Louis, MO 63110, USA.
Samantha A MurphyDepartment of Neurology, Washington University in St. Louis, St. Louis, MO 63110, USA.
Hailee DomashDepartment of Neurology, Washington University in St. Louis, St. Louis, MO 63110, USA.
Shahida AshrafDepartment of Neurology, Washington University in St. Louis, St. Louis, MO 63110, USA.
Andrew J AschenbrennerDepartment of Neurology, Washington University in St. Louis, St. Louis, MO 63110, USA.
Suzanne E SchindlerDepartment of Neurology, Washington University in St. Louis, St. Louis, MO 63110, USA.
Tammie L S BenzingerKnight Alzheimer Disease Research Center, Washington University School of Medicine, St Louis, MO 63110, USA.
John C MorrisDepartment of Neurology, Washington University in St. Louis, St. Louis, MO 63110, USA.
Beau M AncesDepartment of Neurology, Washington University in St. Louis, St. Louis, MO 63110, USA.
Ganesh M BabulalDepartment of Neurology, Washington University in St. Louis, St. Louis, MO 63110, USA.

Funding

Project 1U19AG024904 · NIA · NORTHERN CALIFORNIA INSTITUTE/RES/EDU · PI William J. Jagust · 2016 to 2026
$226.7M
Alzheimer's Disease Neuroimaging Initiative - SupplementU01AG024904 · NIA · NORTHERN CALIFORNIA INSTITUTE RES &EDUC · PI WEINER, MICHAEL W · 2004 to 2015
$121.0M
Smartphone-Based "Burst" Cognitive AssessmentsP01AG003991 · NIA · WASHINGTON UNIVERSITY · PI JOHN MORRIS · 1985 to 2026
$69.5M
Imaging CoreU19AG032438 · NIA · WASHINGTON UNIVERSITY · PI BATEMAN, RANDALL J · 2010 to 2025
$53.9M
The natural history of AB accumulation in preclinical ADP01AG026276 · NIA · WASHINGTON UNIVERSITY · PI MORRIS, JOHN · 2005 to 2025
$49.5M
Washington University Institute of Clinical and Translational SciencesUL1TR000448 · NCATS · WASHINGTON UNIVERSITY · PI EVANOFF, BRADLEY A · 2012 to 2016
$41.4M
Research Education ComponentP30AG066444 · NIA · WASHINGTON UNIVERSITY · PI DAVID M. HOLTZMAN · 2020 to 2026
$28.7M
Naturalistic driving as a functional neurobehavioral marker of preclinical and symptomatic Alzheimer diseaseR01AG068183 · NIA · WASHINGTON UNIVERSITY · PI BABULAL, GANESH M · 2020 to 2024
$6.7M
Imaging CoreU01AG032438 · NIA · WASHINGTON UNIVERSITY · PI MORRIS, JOHN · 2008 to 2009
$6.1M
Preclinical Alzheimer Disease and DrivingR01AG056466 · NIA · WASHINGTON UNIVERSITY · PI BABULAL, GANESH M · 2017 to 2021
$5.9M
The Impact of Depression and Preclinical Alzheimer Disease on Driving Among Older AdultsR01AG067428 · NIA · WASHINGTON UNIVERSITY · PI BABULAL, GANESH M · 2020 to 2024
$4.0M
Aging Research Characterizing Health Exposome via Social drivers (ARCHES)R01AG074302 · NIA · WASHINGTON UNIVERSITY · PI BABULAL, GANESH M · 2021 to 2025
$3.7M
NCATS NIH HHS UL1 TR000448NIA NIH HHS P01 AG003991NIA NIH HHS P01 AG026276NIA NIH HHS P30 AG066444NIA NIH HHS R01 AG043434NIA NIH HHS R01 AG056466NIA NIH HHS R01 AG067428NIA NIH HHS R01 AG068183NIA NIH HHS R01 AG074302NIA NIH HHS U01 AG024904NIA NIH HHS U01 AG032438NIA NIH HHS U19 AG024904NIA NIH HHS U19 AG032438NINR NIH HHS R01 NR012657NINR NIH HHS R01 NR012907NINR NIH HHS R01 NR014449
6 · The paper itself

Abstract

The driving populace of the United States is aging. The prevalence of Alzheimer disease (AD) will increase in the coming decades. Road diets (that is, the reallocation of one or more lanes of car traffic to other uses) have been proposed as a modification to increase pedestrian safety, particularly for older adults. In contrast, we considered the impacts of road diets on aging drivers, and on those with early pathological accumulation of AD. We observed naturalistic driving data for 60 cognitively normal older drivers (Age Range = 62 - 87 years, Median = 75 years) driving across three road segments located in the St. Louis metropolitan area, Missouri, United States. We used neuroimaging and lumbar puncture derived biomarker data to determine which of the drivers had preclinical AD. Since previous AD studies identified a variety of changes in driving behavior among older drivers with preclinical AD, we examined driving speed before and after lane repurposing. We found that drivers with preclinical AD drove at lower speeds compared to those without preclinical AD prior to road diet implementation. After lanes were repurposed, there was no statistical difference in the speed between older drivers with and without preclinical AD. We evaluated cognitive performance and found that attentional control had a mediating effect on driver speed, suggesting that an individual's ability to focus on a specific task and filter out distractions was associated with faster driving. Driving speed after lane repurposing is not mediated by attentional control, suggesting that road diets are impervious to individual driver capacity. We conclude that lane repurposing has potential as an important mobility infrastructure solution that could enhance older driver safety and facilitate aging in place.

Indexed as

agingAlzheimer diseasebiomarkersNaturalistic drivingOlder adultspolicyRoad Diets

Identifiers

PMID40589792
PMCPMC12207637

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.