Evidence map›Paper›PMID 40589790›Full record

ArticleInternational journal of breast cancer2025

Bilateral Primary Breast Cancer With Discordance in Molecular Subtypes: A Case Report.

Yingying Rao, Qian Zhan, Hengyu Li

Abstract readCase Reports
In one paragraph

Article in International journal of breast cancer, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Yingying RaoDepartment of Breast and Thyroid Surgery, The First Affiliated Hospital of Naval Medical University, Shanghai, China.ORCID https://orcid.org/0009-0003-4248-8745
Qian ZhanDepartment of Imaging, The First Affiliated Hospital of Naval Medical University, Shanghai, China.
Hengyu LiDepartment of Breast and Thyroid Surgery, The First Affiliated Hospital of Naval Medical University, Shanghai, China.ORCID https://orcid.org/0000-0002-1007-6493

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Molecular subtype is a crucial prognostic factor for bilateral breast cancer and plays a key role in guiding treatment decisions. Several studies have confirmed that the expression patterns of hormone receptor and human epidermal growth factor receptor 2 are generally consistent in synchronous bilateral primary breast cancer. Discordance in the receptor expression status is commonly associated with poorer prognosis in synchronous bilateral breast cancer. However, there is currently limited literature reporting such cases. This article presents a case of synchronous bilateral primary breast cancer with discordant molecular subtypes and reviews relevant literature.

Identifiers

PMID40589790
PMCPMC12208771

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.