Evidence map›Paper›PMID 40589744›Full record

ReviewFrontiers in immunology2025

Management of infection and ocular complications in pediatric SJS/TEN-like acute graft-versus-host disease: a clinical case study and literature review.

Huimin Yan, Yunjun Mo, Yue Li, Qian Li, Liping Luo, Qing Meng, Lei Jia, Lintao Zhou, Lixia Xiao, Xiaoying Fu

Abstract readCase ReportsReview
In one paragraph

Review in Frontiers in immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Huimin Yan *Department of Laboratory Medicine, Shenzhen Children's Hospital, Shenzhen, GuangDong, China.
Yunjun Mo *Center of Clinical Laboratory, Shenzhen Hospital, Southern Medical University, Shenzhen, GuangDong, China.
Yue LiDepartment of Pediatric Hematology & Oncology, Shenzhen Children's Hospital, Shenzhen, GuangDong, China.
Qian LiDepartment of Pediatric Hematology & Oncology, Shenzhen Children's Hospital, Shenzhen, GuangDong, China.
Liping LuoDepartment of Laboratory Medicine, Shenzhen Children's Hospital, Shenzhen, GuangDong, China.
Qing MengDepartment of Laboratory Medicine, Shenzhen Children's Hospital, Shenzhen, GuangDong, China.
Lei JiaCenter for Regenerative Medicine and Restorative Materials, Huangpu Institute of Materials, Guangzhou, China.
Lintao ZhouDepartment of Laboratory Medicine, Shenzhen Children's Hospital, Shenzhen, GuangDong, China.
Lixia XiaoDepartment of Laboratory Medicine, Shenzhen Children's Hospital, Shenzhen, GuangDong, China.
Xiaoying FuDepartment of Laboratory Medicine, Shenzhen Children's Hospital, Shenzhen, GuangDong, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acute graft-versus-host disease (aGVHD) with skin manifestations reminiscent of Stevens-Johnson Syndrome (SJS) and Toxic Epidermal Necrolysis (TEN) is associated with poor outcomes. However, optimal management strategies to enhance quality of life in SJS/TEN-like aGVHD remain undefined. This study aims to investigate the management of complex infections and acute ocular injury in patients with SJS/TEN-like aGVHD following allogeneic hematopoietic stem cell transplantation. We conducted a comprehensive analysis of the treatment course for a patient with SJS/TEN-like aGVHD, complemented by a literature review on acute ocular complications and their management in aGVHD patients. A patient diagnosed with grade IV skin aGVHD received effective treatment for multidrug-resistant

Indexed as

Eye DiseasesGraft vs Host DiseaseHematopoietic Stem Cell TransplantationStevens-Johnson SyndromeAcute DiseaseChildHumansStenotrophomonas maltophiliaacute graft-versus-host diseaseacute ocular graft-versus-host diseasefungiinfectiontoxic epidermal necrolysis

Identifiers

PMID40589744
PMCPMC12206640

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.