Evidence map›Paper›PMID 40589730›Full record

ArticleFrontiers in veterinary science2025

Antiviral activity of nitazoxanide against pseudorabies virus infection

Lei Tan, Pei Zhu, Zhaori Getu, Xi Yang, Shiling Zheng, Yuqing Duan, Jinping Wang, Yi Zhou, Yuyang Hu, Yijing Wang and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in veterinary science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Lei Tan *College of Animal Science and Technology, Yangtze University, Jingzhou, Hubei, China.
Pei Zhu *Yunnan Tropical and Subtropical Animal Virus Diseases Laboratory, Yunnan Animal Science and Veterinary Institute, Kunming, Yunnan, China.
Zhaori Getu *Chifeng Academy of Agricultural and Animal Husbandry, Chifeng, Inner Mongolia, China.
Xi YangCollege of Animal Science and Technology, Yangtze University, Jingzhou, Hubei, China.
Shiling ZhengCollege of Animal Science and Technology, Yangtze University, Jingzhou, Hubei, China.
Yuqing DuanCollege of Animal Science and Technology, Yangtze University, Jingzhou, Hubei, China.
Jinping WangYunnan Tropical and Subtropical Animal Virus Diseases Laboratory, Yunnan Animal Science and Veterinary Institute, Kunming, Yunnan, China.
Yi ZhouHunan Provincial Key Laboratory of the TCM Agricultural Biogenomics, Changsha Medical University, Changsha, Hunan, China.
Yuyang HuCollege of Animal Science and Technology, Yangtze University, Jingzhou, Hubei, China.
Yijing WangCollege of Animal Science and Technology, Yangtze University, Jingzhou, Hubei, China.
Yuying YangCollege of Animal Science and Technology, Yangtze University, Jingzhou, Hubei, China.
Mengting ZuoHunan Provincial Key Laboratory of the TCM Agricultural Biogenomics, Changsha Medical University, Changsha, Hunan, China.
Jun YaoYunnan Tropical and Subtropical Animal Virus Diseases Laboratory, Yunnan Animal Science and Veterinary Institute, Kunming, Yunnan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pseudorabies (PR), an infectious disease caused by pseudorabies virus (PRV), has been responsible for substantial economic losses within the global swine industry. However, effective control measures and vaccines against PRV remain limited, thereby underscoring the necessity for the development of innovative antiviral agents targeting PRV. Nitazoxanide (NTZ) is an FDA-approved anthelminthic drug, has shown efficacy in inhibiting a variety of viral infections. This study aims to evaluate the antiviral properties of NTZ against PRV infection

Indexed as

antiviral activitynitazoxanidepseudorabies virusRNA-Seqviral replication phase

Identifiers

PMID40589730
PMCPMC12206632

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.