Evidence map›Paper›PMID 40589651›Full record

SynthesisFrontiers in psychiatry2025

Quality appraisal of clinical practice guidelines for attention deficit hyperactivity disorder: a systematic review using the appraisal of guidelines for research and evaluation (AGREE II) instrument.

Muhammad Dwi Wahyu, Atsunori Sugimoto, Ekachaeryanti Zain, Faisal Budisasmita Paturungi Parawansa, Hiroyuki Kasahara, Kiyohiro Yoshinaga, Jun Egawa

Abstract readSystematic Review
In one paragraph

Synthesis in Frontiers in psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Muhammad Dwi WahyuDepartment of Psychiatry, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.
Atsunori SugimotoDepartment of Community Psychiatric Medicine, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.
Ekachaeryanti ZainDepartment of Psychiatry, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.
Faisal Budisasmita Paturungi ParawansaDepartment of Psychiatry, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.
Hiroyuki KasaharaDepartment of Community Psychiatric Medicine, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.
Kiyohiro YoshinagaDepartment of Psychiatry, Niigata University Medical and Dental Hospital, Niigata, Japan.
Jun EgawaDepartment of Psychiatry, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: Attention deficit hyperactivity disorder (ADHD) can significantly impact multiple life conditions across the lifespan. Reliable clinical practice guidelines (CPGs) are crucial for the clinical decision-making for the diagnosis and management of ADHD. This study aimed to assess the quality of current CPGs for the diagnosis and management of ADHD. Methods: We conducted a systematic literature search within Pubmed, Google Scholar, the Agency for Healthcare Research and Quality, Dynamed, the National Institute for Health and Care Excellence (NICE), the National Health and Medical Research Council (NHMRC), and other local and online databases started January 19, 2022. We assessed the guideline quality using the Appraisal of Guidelines for Research and Evaluation (AGREE II) instrument. All of the included guidelines were critically appraised by five independent reviewers. We also evaluated the interrater reliability of each AGREE II domain and the overall domain score by calculating the intraclass correlation coefficient (ICC) using IBM SPSS Statistics version 28. Results: A total of 11 CPGs were included in the study. The majority of the CPGs achieved the highest score in domain 4 "Clarity of Presentation" (mean ± standard deviation, 73.73% ± 12.5%). The domains that achieved the lowest scores were domains 5 "Applicability" (mean ± standard deviation, 45.18% ± 16.4%) and 3 "Rigor of Development" (mean ± standard deviation, 51.09% ± 24.1%). The American Academy of Pediatrics (AAP), NICE, and the Malaysian Health Technology Assessment Section (MAHTAS) CPGs were identified as the strongly recommended guidelines. All AGREE II domains yielded varied interrater reliability results; the full domain ICC ranged from 0.265 (95% confidence interval, -0.470 to 0.665) to 0.758 (95% confidence interval, 0.515 to 0.889). Conclusions: Our appraisal indicated that the quality of current ADHD guidelines is varied, and three CPGs were classified as strongly recommended. Our findings offer relevant healthcare providers valuable insight into the appropriate selection of ADHD guidelines in clinical practice. Systematic review registration: https://inplasy.com/inplasy-2022-8-0001/, identifier INPLASY202280001.

Indexed as

ADHDAGREE IIguidelinePRISMAsystematic review

Identifiers

PMID40589651
PMCPMC12206699

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.