ReviewFrontiers in oncology2025
Photodynamic therapy and nanomedicine: current knowledge, limitations, and applications in oral squamous cell carcinoma: a narrative review.
Review in Frontiers in oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
4 citing papers in PubMed.
- Photodynamic Therapy in Cancer: Mechanisms, Photosensitizer Technology, Vitamin Modulation, and Rational Combination Design.Biomedicines · 2026Review
- Evaluation of Antitumor and Antimicrobial Photobiological Activity of Nanocarrier Containing Photosensitizer and Magnetic Nanoparticle.Current issues in molecular biology · 2026Article
- The application of ICG-based photodynamic therapy combined with nanotechnology in tumor treatment.RSC advances · 2026Review
- Delineating precise surgical resection areas: recent advances in NIR-II fluorescence imaging molecular probes.Frontiers in oncology · 2026Review
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Oral squamous cell carcinoma is still a global health issue, even if oral cavity is an easily accessible anatomical site, the diagnosis is still delayed. Conventional treatments, like chemotherapy and radiotherapy, are usually employed, but not without complications. These drawbacks have necessitated the need for new therapies, one of these is photodynamic therapy (PDT). Nanotechnologies-enhanced PDT has significantly improved tumor targeting, bioavailability, and light absorption, paving the way for its application in early-stage of oral squamous cell carcinoma (OSCC) and as part of combination therapies for advanced cases. Despite the potential advantages of PDT, such as tumor selectivity, minimization of systemic side effects and repeatability of treatment, some limitations still restrict its clinical application. Despite these challenges, its application in oral squamous cell carcinoma and oral potentially malignant disease is promising, both alone or in combination with other therapies. Addressing such pros and cons of this technique, PDT may then be a possible adjuvant tool in the management of OSCC.
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Registered trials
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