Evidence map›Paper›PMID 40589618›Full record

ArticleDEN open2026

Gel Immersion Endoscopic Submucosal Dissection Using a Scissor-type Knife for Superficial Non-ampullary Duodenal Epithelial Tumors.

Osamu Dohi, Naoto Iwai, Hayato Fukui, Mayuko Seya, Tomoko Ochiai, Junki Yumoto, Hiroki Mukai, Katsuma Yamauchi, Hajime Miyazaki, Takeshi Yasuda and 12 more

Abstract read
In one paragraph

Article in DEN open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Clinical Outcomes of Underwater Endoscopic Submucosal Dissection for Duodenal Tumors: A Systematic Review and Meta-Analysis.Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society · 2026
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Osamu DohiMolecular Gastroenterology and Hepatology Graduate School of Medical Science Kyoto Prefectural University of Medicine Kyoto Japan.ORCID https://orcid.org/0000-0002-0498-0144
Naoto IwaiMolecular Gastroenterology and Hepatology Graduate School of Medical Science Kyoto Prefectural University of Medicine Kyoto Japan.
Hayato FukuiMolecular Gastroenterology and Hepatology Graduate School of Medical Science Kyoto Prefectural University of Medicine Kyoto Japan.
Mayuko SeyaMolecular Gastroenterology and Hepatology Graduate School of Medical Science Kyoto Prefectural University of Medicine Kyoto Japan.
Tomoko OchiaiMolecular Gastroenterology and Hepatology Graduate School of Medical Science Kyoto Prefectural University of Medicine Kyoto Japan.
Junki YumotoMolecular Gastroenterology and Hepatology Graduate School of Medical Science Kyoto Prefectural University of Medicine Kyoto Japan.
Hiroki MukaiMolecular Gastroenterology and Hepatology Graduate School of Medical Science Kyoto Prefectural University of Medicine Kyoto Japan.
Katsuma YamauchiMolecular Gastroenterology and Hepatology Graduate School of Medical Science Kyoto Prefectural University of Medicine Kyoto Japan.
Hajime MiyazakiMolecular Gastroenterology and Hepatology Graduate School of Medical Science Kyoto Prefectural University of Medicine Kyoto Japan.
Takeshi YasudaMolecular Gastroenterology and Hepatology Graduate School of Medical Science Kyoto Prefectural University of Medicine Kyoto Japan.
Takuma YoshidaMolecular Gastroenterology and Hepatology Graduate School of Medical Science Kyoto Prefectural University of Medicine Kyoto Japan.
Tsugitaka IshidaMolecular Gastroenterology and Hepatology Graduate School of Medical Science Kyoto Prefectural University of Medicine Kyoto Japan.
Hiroaki KitaeMolecular Gastroenterology and Hepatology Graduate School of Medical Science Kyoto Prefectural University of Medicine Kyoto Japan.ORCID https://orcid.org/0000-0002-7103-8191
Yukiko MorinagaDepartment of Surgical Pathology Graduate School of Medical Science Kyoto Prefectural University of Medicine Kyoto Japan.
Reo KobayashiMolecular Gastroenterology and Hepatology Graduate School of Medical Science Kyoto Prefectural University of Medicine Kyoto Japan.
Ryohei HiroseDepartment of Infectious Diseases Graduate School of Medical Science Kyoto, Prefectural University of Medicine Kyoto Japan.
Ken InoueMolecular Gastroenterology and Hepatology Graduate School of Medical Science Kyoto Prefectural University of Medicine Kyoto Japan.
Naohisa YoshidaMolecular Gastroenterology and Hepatology Graduate School of Medical Science Kyoto Prefectural University of Medicine Kyoto Japan.ORCID https://orcid.org/0000-0001-6167-9705
Kazuhiko UchiyamaMolecular Gastroenterology and Hepatology Graduate School of Medical Science Kyoto Prefectural University of Medicine Kyoto Japan.
Tomohisa TakagiMolecular Gastroenterology and Hepatology Graduate School of Medical Science Kyoto Prefectural University of Medicine Kyoto Japan.
Hideyuki KonishiMolecular Gastroenterology and Hepatology Graduate School of Medical Science Kyoto Prefectural University of Medicine Kyoto Japan.
Yoshito ItohMolecular Gastroenterology and Hepatology Graduate School of Medical Science Kyoto Prefectural University of Medicine Kyoto Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: This study aimed to compare the short-term therapeutic outcomes between conventional endoscopic submucosal dissection (C-ESD) and gel immersion ESD (GI-ESD) for superficial non-ampullary duodenal epithelial tumors (SNADETs). Methods: A retrospective analysis was conducted on patients with SNADETs who underwent C-ESD or GI-ESD between June 2016 and May 2024. To reduce proficiency bias, the first 50 cases per endoscopist were excluded. C-ESD was performed using a scissor-type knife under CO Results: Overall, 51 C-ESD and 49 GI-ESD procedures were analyzed. Both groups achieved 100% en bloc resection. R0 resection rates were comparable (C-ESD: 92.6%, GI-ESD: 90.2%, Conclusions: GI-ESD is a safe and effective alternative to conventional ESD for SNADETs, offering comparable resection outcomes and low risk of adverse events with a reduced risk of muscle layer exposure.

Indexed as

adverse event | endoscopic submucosal dissection | gel immersion | scissor‐type knife | superficial non‐ampullary duodenal epithelial tumor

Identifiers

PMID40589618
PMCPMC12208102

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.