Evidence map›Paper›PMID 40589535›Full record

ArticleFrontiers in surgery2025

Nomogram for prediction of recurrence in patients with lumbar disc herniation after unilateral biportal endoscopy spinal surgery: a retrospective study.

Yi Rong, Kaixuan Wang, Yalan Pan, Tianchi Zhang, Yong Ma, Lining Wang, Yang Guo, Si Chen, Yang Shao, Tingchen Zhu and 4 more

Abstract read
In one paragraph

Article in Frontiers in surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Yi Rong *Department of Traumatology & Orthopedics, Wuxi Affiliated Hospital of Nanjing University of Chinese Medicine, Wuxi, China.
Kaixuan Wang *School of Integrative Medicine, Nanjing University of Chinese Medicine, Nanjing, Jiangsu, China.
Yalan Pan *Laboratory of New Techniques of Restoration & Reconstruction, Institute of Traumatology & Orthopedics, Nanjing University of Chinese Medicine, Nanjing, China.
Tianchi ZhangLaboratory of New Techniques of Restoration & Reconstruction, Institute of Traumatology & Orthopedics, Nanjing University of Chinese Medicine, Nanjing, China.
Yong MaSchool of Integrative Medicine, Nanjing University of Chinese Medicine, Nanjing, Jiangsu, China.
Lining WangSchool of Integrative Medicine, Nanjing University of Chinese Medicine, Nanjing, Jiangsu, China.
Yang GuoLaboratory of New Techniques of Restoration & Reconstruction, Institute of Traumatology & Orthopedics, Nanjing University of Chinese Medicine, Nanjing, China.
Si ChenDepartment of Traumatology & Orthopedics, Wuxi Affiliated Hospital of Nanjing University of Chinese Medicine, Wuxi, China.
Yang ShaoDepartment of Traumatology & Orthopedics, Wuxi Affiliated Hospital of Nanjing University of Chinese Medicine, Wuxi, China.
Tingchen ZhuDepartment of Traumatology & Orthopedics, Wuxi Affiliated Hospital of Nanjing University of Chinese Medicine, Wuxi, China.
Shixiang WuDepartment of Traumatology & Orthopedics, Wuxi Affiliated Hospital of Nanjing University of Chinese Medicine, Wuxi, China.
Zhen HuaDepartment of Traumatology & Orthopedics, Wuxi Affiliated Hospital of Nanjing University of Chinese Medicine, Wuxi, China.
Jianwei WangDepartment of Traumatology & Orthopedics, Wuxi Affiliated Hospital of Nanjing University of Chinese Medicine, Wuxi, China.
Hao YuDepartment of Traumatology & Orthopedics, Wuxi Affiliated Hospital of Nanjing University of Chinese Medicine, Wuxi, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: This study aimed to construct a nomogram to predict the likelihood of early recurrence in patients with lumbar disc herniation (LDH) following unilateral biportal endoscopic (UBE) surgery. Methods: A retrospective analysis was conducted on LDH patients who underwent UBE surgery in our department between January 1, 2022, and December 31, 2023. The eligible cohort was randomly divided into training and validation sets in a 7:3 ratio. Key predictors for the nomogram were identified through a combination of least absolute shrinkage and selection operator (LASSO) regression and multivariate logistic regression analysis. The model's performance was assessed using the C-index, the area under the receiver operating characteristic curve (AUC), calibration curves, and decision curve analysis. The validation set was used to further evaluate the model's robustness. Results: A total of 289 patients were included in the study, among whom 50 experienced recurrent LDH (rLDH). Five risk factors were identified as significant predictors for rLDH: width of protrusion base (WPB), bone removal range (BRR), Modic changes, type of LDH, and middle vertebral space height (MVH). The C-index values for the training and validation sets were 0.834 and 0.804, respectively. The AUC values were 0.834 (95% CI: 0.750-0.918) in the training set and 0.804 (95% CI: 0.697-0.910) in the validation set. Calibration curves demonstrated excellent concordance between the predicted and observed outcomes. Decision curve analysis indicated that using the nomogram to predict rLDH risk provided a positive net benefit when the threshold probability was between 4% and 63%. Conclusion: This study successfully developed and validated a nomogram to predict early recurrence in LDH patients following UBE surgery. The model provides a valuable tool for clinicians to assess individual rLDH risk, enabling timely interventions to improve postoperative outcomes.

Indexed as

LDHnomogramprediction modelrecurrenceUBE

Identifiers

PMID40589535
PMCPMC12206763

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.