Evidence map›Paper›PMID 40589221›Full record

ArticleACS applied bio materials2025

Bifunctional Metal Ion-Enhanced PDA-Coated Titanium for Superior Osteogenic and Antimicrobial Performance.

Chenhui Liu, Sikun Meng, Huachun Wang, Tianzhen Zhang, Cheng Qi, Mei Li, Jingyang Kang

Abstract read
In one paragraph

Article in ACS applied bio materials, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Chenhui LiuKey Laboratory for Liquid Solid Structural Evolution and Processing of Materials (Ministry of Education), School of Materials Science and Engineering, Shandong University, 17923 Jingshi Road, Jinan, Shandong 250061, People's Republic of China.ORCID 0009-0001-0314-6406
Sikun MengDepartment of Medical Data Science, Center of Medical Innovation and Translational Research, Osaka University Graduate School of Medicine, Suita, Yamadaoka 2-2, Osaka 565-0871, Japan.
Huachun WangDepartment of Stomatology, Qilu Hospital (Qingdao), Cheeloo College of Medicine, Shandong University, 758 Hefei Road, Qingdao, Shandong 266035, People's Republic of China.
Tianzhen ZhangDepartment of Stomatology, Qilu Hospital (Qingdao), Cheeloo College of Medicine, Shandong University, 758 Hefei Road, Qingdao, Shandong 266035, People's Republic of China.
Cheng QiDepartment of Stomatology, Shandong Provincial Third Hospital, Shandong University, 11 Wuyingshan Middle Road, Jinan, Shandong 250031, People's Republic of China.
Mei LiDepartment of Stomatology, Shandong Provincial Third Hospital, Shandong University, 11 Wuyingshan Middle Road, Jinan, Shandong 250031, People's Republic of China.
Jingyang KangDepartment of Stomatology, Qilu Hospital (Qingdao), Cheeloo College of Medicine, Shandong University, 758 Hefei Road, Qingdao, Shandong 266035, People's Republic of China.ORCID 0000-0001-5792-5918

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Titanium (Ti) implants serve as a popular solution for tooth replacement, because they combine excellent mechanical properties with high biocompatibility. However, the biologically inert nature of titanium surfaces restricts their osteogenic capacity and renders them prone to bacterial colonization, elevating the risk of biofilm formation and implant-associated infections. Surface modification of titanium implants is essential to overcoming these limitations. To optimize the titanium surface functionality, this study employed a polydopamine (PDA) coating strategy combined with subsequent incorporation of copper and manganese ions. We prepared Ti-PDA and then fabricated Ti-PDA-Cu and Ti-PDA-Cu/Mn samples. Material characterization revealed that Ti-PDA-Cu/Mn exhibits favorable surface wettability and biocompatibility, along with sustained and stable release of Cu

Indexed as

Anti-Bacterial AgentsCoated Materials, BiocompatibleIndolesOsteogenesisPolymersTitaniumAnimalsCell ProliferationCopperEscherichia coliHumansIonsManganeseMaterials TestingMiceMicrobial Sensitivity TestsAnti-Bacterial AgentsCoated Materials, BiocompatibleCopperIndolesIonsManganesepolydopaminePolymersTitaniumantibacterialbiomaterialsbone regenerationcoatingdental implantpolydopaminetitanium

Identifiers

PMID40589221
PMCPMC12285667

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.