Evidence map›Paper›PMID 40589194›Full record

ArticleInterventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences2025

Microguidewire stiffness for microcatheter and aspiration catheter navigation in tortuous vessels.

Kenichi Sakuta, Yoshiki Hanaoka, Mahsa Ghovvati, Amir Molaie, Taichiro Imahori, Keiko A Fukuda, Satoshi Tateshima, Naoki Kaneko

Abstract read
In one paragraph

Article in Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Kenichi SakutaDepartment of Neurology, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.ORCID 0000-0002-7125-7482
Yoshiki HanaokaDepartment of Radiological Sciences, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.
Mahsa GhovvatiDepartment of Radiological Sciences, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.ORCID 0000-0002-0608-5768
Amir MolaieDepartment of Neurology, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.ORCID 0000-0001-7184-8613
Taichiro ImahoriDepartment of Radiological Sciences, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.ORCID 0000-0002-8744-3044
Keiko A FukudaDepartment of Radiological Sciences, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.ORCID 0000-0001-6057-2447
Satoshi TateshimaDepartment of Radiological Sciences, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.ORCID 0000-0003-0060-0930
Naoki KanekoDepartment of Radiological Sciences, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.ORCID 0000-0002-3579-7908

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BackgroundEffective catheter navigation and trackability are crucial in neuroendovascular procedures, particularly through tortuous vessels where catheter kickback can potentially delay treatment and worsen patient outcomes. While operational experience suggests that stiffer microguidewires enhance catheter navigation and trackability, this relationship has not been experimentally validated. This study assesses the impact of microguidewire stiffness on targeted catheter delivery using in-vitro vascular models with severe tortuosity.MethodsTwo experiments were conducted using silicone models of the intracranial vasculature to evaluate microguidewires of similar composition but differing stiffness, as defined by greater resistance to bending with the Stryker Synchro Select Soft, Standard, and Support microguidewires. In Experiment 1, 0.021″ microcatheter navigation through an acute angle M2 branch of the middle cerebral artery was assessed. In Experiment 2, 0.071″ aspiration catheter navigation through a severely tortuous internal carotid artery model was tested. Maximum catheter pushing force and microguidewire kickback length were measured in both experiments.ResultsStiffer microguidewires required significantly lower pushing forces and exhibited reduced microwire kickback during both microcatheter and aspiration catheter advancement.ConclusionsMicroguidewire stiffness significantly influences neuroendovascular catheter deliverability. Stiffer microguidewires provide greater system stability, particularly at the distal end, enhancing catheter navigation and advancement through tortuous anatomy.

Indexed as

aspiration catheterDevice navigationmicrocathetermicroguidewiretortuous anatomy

Identifiers

PMID40589194
PMCPMC12213524

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.