Evidence map›Paper›PMID 40589104›Full record

ArticleJournal of veterinary science2025

Detection and genetic evolution analysis of porcine reproductive and respiratory syndrome virus in Chengdu from January 2021 to December 2022.

Hongyu Zhong, Kerong Li, Min Li, Kun Zhang, Yi Zhang, Luqi Liang, Haifeng Liu, Zhijun Zhong, Guangneng Peng, Xiaoxiao Zhou and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of veterinary science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Hongyu Zhong *Department of Clinical Veterinary Medicine, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China.ORCID https://orcid.org/0009-0005-0607-1752
Kerong Li *Department of Clinical Veterinary Medicine, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China.ORCID https://orcid.org/0000-0002-2905-4139
Min Li *Chengdu Center for Animal Disease Prevention and Control, Chengdu 610041, China.ORCID https://orcid.org/0009-0000-3917-4444
Kun ZhangDepartment of Clinical Veterinary Medicine, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China.ORCID https://orcid.org/0009-0008-8037-7735
Yi ZhangSichuan Center for Animal Disease Prevention and Control, Chengdu 610041, China.ORCID https://orcid.org/0009-0006-3554-7091
Luqi LiangSichuan Center for Animal Disease Prevention and Control, Chengdu 610041, China.ORCID https://orcid.org/0009-0003-3522-0521
Haifeng LiuDepartment of Clinical Veterinary Medicine, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China.ORCID https://orcid.org/0000-0002-7495-9332
Zhijun ZhongDepartment of Clinical Veterinary Medicine, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China.ORCID https://orcid.org/0000-0001-8609-448X
Guangneng PengDepartment of Clinical Veterinary Medicine, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China.ORCID https://orcid.org/0000-0002-9898-5754
Xiaoxiao ZhouChengdu Center for Animal Disease Prevention and Control, Chengdu 610041, China. spongebob19891104@gmail.com.ORCID https://orcid.org/0000-0002-7767-5271
Ziyao ZhouDepartment of Clinical Veterinary Medicine, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China.ORCID https://orcid.org/0000-0002-8947-4303

Funding

Sichuan Province Science and Technology Support Program 2021ZDZX0010
6 · The paper itself

Abstract

importancePandemics involving the porcine reproductive and respiratory syndrome virus (PRRSV) impact swine health and productivity, causing economic devastation, especially in large-scale feeding areas.

objectiveThis study examined the prevalence and genetic variations of PRRSV in Chengdu, China, a vital transportation hub and the main area of pig breeding in southwest China, between January 2021 and December 2022.

methodsThe samples were collected from 13 key pig-feeding areas in Chengdu. The positive PRRSV samples were detected using a real-time quantitative polymerase chain reaction. The genetic variations of the PRRSV were analyzed by amplifying the open reading frame 5 (ORF5) gene and comparing it with relevant reference sequences.

resultsThe PRRSV positive rate in Chengdu was 11.42% (276/2,416), including sublines 8.7, 5.1, 3.0, and 1.8. The ORF5 gene sequences in the samples had no insertion or deletion of amino acids but widespread variations, including the 13th and 151st positions, which were associated with viral virulence. CONCLUSIONS AND RELEVANCE: The PRRSV pandemic in Chengdu was relevant, and recombination between vaccine strains and field strains can contribute to vaccine immune failure.

Indexed as

Evolution, MolecularGenetic VariationPorcine Reproductive and Respiratory SyndromePorcine respiratory and reproductive syndrome virusAnimalsChinaPhylogenyPrevalenceSwineepidemicsgenetic evolutionORF5 genePRRSV

Identifiers

PMID40589104
PMCPMC12329057

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.