ArticleMicrobiologyOpen2025
Novel Animal Model of Enterobacteria Pathogenicity, Virulence, and Amoxicillin-Biosurfactant Synergic Using Nsombé (Rhynchophorus phoenicis Larvae).
Article in MicrobiologyOpen, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
6 authors.
Funding
Abstract
Insect larvae are increasingly being employed as sophisticated infection models in the expanding field of pathogenic bacterial research. This innovative study aims to evaluate an alternative model for analyzing host-pathogen interactions and assessing the efficacy of antimicrobial treatments using the biological system of Rhynchophorus phoenicis larvae. Using PCR techniques targeting 16S rRNA, virulence genes encoding Type III secretion system (T3SS) components, and the Hsp60 gene, four major pathogenic Enterobacteriaceae were identified with 100% detection rates: Salmonella Typhimurium, Klebsiella pneumoniae, Enterobacter cloacae, and enteropathogenic Escherichia coli (EPEC). Virulence assessment revealed that injection of bacterial strains at a concentration of 10
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