ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2025
Navigating parenthood and a partner's terminal cancer: subgroup analysis of the course of psychological distress within a comprehensive support program for families with parental cancer (Family-SCOUT).
Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04186923 (Familien-SCOUT), which is not on this map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Familien-SCOUT: Comprehensive Support for Families With a Parent Suffering From Cancer
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Authors and funding
12 authors.
Funding
Abstract
purposeCaregivers of terminally ill cancer patients are acknowledged to be at a heightened risk for experiencing severe psychological distress. This study examines psychological distress in healthy parents (HPs) caring for both a partner in the end-of-life phase and dependent children and how the Family-SCOUT intervention affects their distress course.
methodsThis analysis utilized data from the multicenter, quasi-experimental, non-randomized, non-blinded Family-SCOUT intervention study. HPs were stratified into subgroups based on their partner's survival status 12 months after T0 (study enrollment) and their assignment to the intervention or control group. Psychological distress was assessed using the Hospital Anxiety and Depression Scale (HADS) at T0 and at T2 (9 months of follow-up). Threshold analysis, t-tests, repeated measures ANOVA, and effect sizes were conducted to evaluate data.
resultsHADS values were available from n = 63 HPs with a terminally ill partner and n = 262 HPs with a partner, who survived 12 months or longer after T0. Overall, the groups were similar apart from the distribution of sex. Distress was high in all subgroups but was especially elevated for HPs with a terminally ill partner. The trajectory of distress was influenced by their partner's survival status and their intervention group allocation. Distress decreased in all subgroups except for HPs with a terminally ill partner not receiving the intervention.
conclusionHPs with a partner in the end-of-life phase are an especially vulnerable subgroup. Family-SCOUT appears beneficial for even highly distressed subgroups, although further research on the cause and the course of their distress is essential.
trial registrationCLINICALTRIALS: gov, NCT04186923, 4th of December 2019, retrospectively registered.
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