Evidence map›Paper›PMID 40588594›Full record

Observational studySupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2025

A longitudinal observational study of demoralization within 6 months following cancer diagnosis: a cross-lagged panel network analysis.

Su Ting Liu, Xin Yi Zhang, Qing Su, Zhi Hui Yang, Li Li Zhang

Abstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Reconsidering the interpretation of network analysis in symptom research.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Su Ting Liu *School of Nursing, Southern Medical University, Baiyun District, No.1023, South Shatai Road, Guangzhou, Guangdong, 510515, China.
Xin Yi Zhang *School of Nursing, Southern Medical University, Baiyun District, No.1023, South Shatai Road, Guangzhou, Guangdong, 510515, China.
Qing SuSchool of Nursing, Southern Medical University, Baiyun District, No.1023, South Shatai Road, Guangzhou, Guangdong, 510515, China.
Zhi Hui YangSchool of Nursing, Southern Medical University, Baiyun District, No.1023, South Shatai Road, Guangzhou, Guangdong, 510515, China.
Li Li ZhangSchool of Nursing, Southern Medical University, Baiyun District, No.1023, South Shatai Road, Guangzhou, Guangdong, 510515, China. zhanglili_gzsmu@163.com.

Funding

China Guangdong Province Science and Technology Project 2017A020215093
6 · The paper itself

Abstract

purposeTo identify the dynamic change and explore the longitudinal correlates of demoralization in patients after cancer diagnosis, provide comprehensive references for interventions targeting demoralization at different time points.

methodsThis study included 127 cancer patients from a tertiary hospital in Guangzhou, China. Demoralization was assessed at three time points: 1 (T1), 3 (T2), and 6 (T3) months after cancer diagnosis. The study employed a cross-lagged panel network analysis to explore the longitudinal interactions in demoralization.

resultsThere were 52%, 55.4%, and 56.0% of the participants reported high demoralization in 1, 3, and 6 months after cancer diagnosis, respectively. In T1-T2, the strongest direct influence was D1 ("There is a lot of value in what I can offer others")-D21 ("I feel sad and miserable") (B = 0.32), D24 ("I feel trapped by what is happening to me") was the most influential in-prediction and out-prediction variable in this cross-lagged network. In T2-T3, the strongest direct influence was D9 ("I feel hopeless")-D13 ("I have a lot of regret about my life") (B = 0.24), and the D9 was the most influential out-prediction variable in the cross-lagged network.

conclusionConsidering feeling trapped and hopelessness reported the highest prediction of other symptoms in T1-T2 and T2-T3, respectively, clinical interventions for demoralization should have specific objectives for different periods.

Indexed as

NeoplasmsAdultAgedChinaFemaleHumansLongitudinal StudiesMaleMiddle AgedTime FactorsCancerCross-lagged panel network analysisDemoralizationLongitudinal study

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.