ReviewActa neurologica Belgica2026
Insights into diagnostics and management of spinal neuroschistosomiasis: A scoping review of 230 cases of a neglected disease.
Review in Acta neurologica Belgica, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Neurochagas: Experimental and human literature of an uncommon entity (Review).Medicine internationalReview
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSchistosomiasis is a neglected tropical disease caused by parasitic worms from the genus Schistosoma. Spinal neuroschistosomiasis (SN) is a rare but serious complication that can result in significant morbidity and mortality, with only a few hundred cases documented in the literature.
methodsFollowing the Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA-ScR) statement, extension for scoping reviews, a systematic search of PubMed, Scopus, and Web of Science using relevant keywords, from inception until November 7th, 2024, was carried out followed by screening and extraction of only detailed cases.
resultsOf 657 reports, 108 reports of 230 detailed cases were finally included. The included patients had a mean (standard deviation) age of 25.22 (14.65) years with most of them being males (79.6%). The majority of our patients (85.7%) got infected in endemic areas. As for clinical presentations, myelitis was the most common syndrome (48.3%) followed by myeloradicular syndrome (33.5%). The dorsal cord was the most frequently affected region, documented in 56.5% of cases. Imaging studies revealed pathological findings in 57.7% with magnetic resonance imaging (MRI) and 34.4% with computed tomography (CT). Cerebrospinal fluid (CSF) findings included elevated protein (47.4%), pleocytosis (26.5%), and eosinophilia (29.6%). Anti-parasitic use was reported in most cases (79.6%) while steroids were attempted in 70.5% of cases. A complete recovery was achieved in 18% of cases. Death was the outcome in 4% of the included patients.
conclusionsDue to delayed diagnosis and rarity, SN causes significant morbidity and mortality with diagnostic challenges and heterogeneity.
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