Evidence map›Paper›PMID 40588370›Full record

ArticleJournal for immunotherapy of cancer2025

Low-dose radiotherapy enhances the efficacy of PD-L1 blockade and induces the abscopal effect.

Pierre-Antoine Laurent, Liu Shi, Lisa Bouarroudj, Nathan Benzazon, Marine Gerbé De Thoré, Winchygn Liu, Marine Aglave, Paul Bergeron, Flavie Naulin, Lisa Sitterlé and 7 more

Abstract read
In one paragraph

Article in Journal for immunotherapy of cancer, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Timing matters: how mechanism-guided sequencing shapes the efficacy of radiotherapy-immunotherapy combinations : A systematic review.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2026
    Review
  6. Review
  7. Review
  8. Article
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  12. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Pierre-Antoine LaurentINSERM U1030 "Molecular Radiotherapy and Therapeutic Innovations", Gustave Roussy, Villejuif, France.ORCID http://orcid.org/0000-0002-1544-5390
Liu ShiINSERM U1030 "Molecular Radiotherapy and Therapeutic Innovations", Gustave Roussy, Villejuif, France.
Lisa BouarroudjINSERM U1030 "Molecular Radiotherapy and Therapeutic Innovations", Gustave Roussy, Villejuif, France.
Nathan BenzazonINSERM U1030 "Molecular Radiotherapy and Therapeutic Innovations", Gustave Roussy, Villejuif, France.
Marine Gerbé De ThoréINSERM U1030 "Molecular Radiotherapy and Therapeutic Innovations", Gustave Roussy, Villejuif, France.
Winchygn LiuINSERM U1030 "Molecular Radiotherapy and Therapeutic Innovations", Gustave Roussy, Villejuif, France.
Marine AglaveBioinformatics Platform, Gustave Roussy, Villejuif, France.
Paul BergeronINSERM U1030 "Molecular Radiotherapy and Therapeutic Innovations", Gustave Roussy, Villejuif, France.
Flavie NaulinINSERM U1030 "Molecular Radiotherapy and Therapeutic Innovations", Gustave Roussy, Villejuif, France.
Lisa SitterléINSERM U1030 "Molecular Radiotherapy and Therapeutic Innovations", Gustave Roussy, Villejuif, France.
Daphné MorelINSERM U1030 "Molecular Radiotherapy and Therapeutic Innovations", Gustave Roussy, Villejuif, France.
Antonin LevyINSERM U1030 "Molecular Radiotherapy and Therapeutic Innovations", Gustave Roussy, Villejuif, France.ORCID http://orcid.org/0000-0003-4798-8899
Céline ClémensonINSERM U1030 "Molecular Radiotherapy and Therapeutic Innovations", Gustave Roussy, Villejuif, France.
Michele MondiniINSERM U1030 "Molecular Radiotherapy and Therapeutic Innovations", Gustave Roussy, Villejuif, France.ORCID http://orcid.org/0000-0001-5803-0083
Charlotte RobertINSERM U1030 "Molecular Radiotherapy and Therapeutic Innovations", Gustave Roussy, Villejuif, France.
Lydia Meziani *INSERM U1030 "Molecular Radiotherapy and Therapeutic Innovations", Gustave Roussy, Villejuif, France eric.deutsch@gustaveroussy.fr lydia.meziani@chuv.ch.ORCID http://orcid.org/0000-0002-1127-0183
Eric Deutsch *INSERM U1030 "Molecular Radiotherapy and Therapeutic Innovations", Gustave Roussy, Villejuif, France eric.deutsch@gustaveroussy.fr lydia.meziani@chuv.ch.ORCID http://orcid.org/0000-0002-8223-3697

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

B7-H1 AntigenImmune Checkpoint InhibitorsImmunotherapyAnimalsCell Line, TumorFemaleHumansMiceTumor MicroenvironmentB7-H1 AntigenImmune Checkpoint InhibitorsAbscopalImmunotherapyMacrophagesRadiotherapy/radioimmunotherapySolid tumor

Identifiers

PMID40588370
PMCPMC12211843

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.