Evidence map›Paper›PMID 40588302›Full record

ArticleBMJ case reports2025

Successful management of recurrent thrombosis of prosthetic mitral valve induced by eosinophilia secondary to parasitic infection.

Ly Nguyen Thi Minh, Hieu Lan Nguyen, Lan Viet L Nguyen, Ngoc Minh N Pham, Hoang Dang, Lan Anh Nguyen, Hoa L Nguyen, Robert J Goldberg

Abstract readCase Reports
In one paragraph

Article in BMJ case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ly Nguyen Thi MinhCardiology, Hanoi Medical University, Hanoi, Viet Nam minhly.ng@gmail.com.ORCID http://orcid.org/0000-0001-8655-3279
Hieu Lan NguyenCardiovascular Center, Hanoi Medical University Hospital, Hanoi, Viet Nam.ORCID http://orcid.org/0000-0003-4302-8612
Lan Viet L NguyenCardiology, Hanoi Medical University, Hanoi, Viet Nam.ORCID http://orcid.org/0009-0002-6780-6394
Ngoc Minh N PhamHanoi Medical University Hospital, Hanoi, Viet Nam.ORCID http://orcid.org/0009-0005-5992-7913
Hoang DangHanoi Medical University Hospital, Hanoi, Viet Nam.ORCID http://orcid.org/0009-0001-8715-3135
Lan Anh NguyenNursing and Midwifery, Hanoi Medical University, Hanoi, Viet Nam.ORCID http://orcid.org/0009-0006-0261-7401
Hoa L NguyenDivision of Epidemiology Department of Population and Quantitative Health Sciences, University of Massachusetts Chan Medical School, Worcester, Massachusetts, USA.ORCID http://orcid.org/0000-0002-4998-8510
Robert J GoldbergPopulation and Quantitative Health Sciences, University of Massachusetts Chan Medical School, Worcester, Massachusetts, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acute prosthetic heart valve thrombosis (PHVT) is a severe complication affecting patients who have undergone heart valve replacement surgery. We present a case of acute recurrent PHVT associated with parasite-induced eosinophilia. A man in his early 50s with rheumatic heart disease underwent mechanical mitral valve replacement 5 years ago and received well-managed anticoagulation with regular follow-up visits. The patient developed a sudden onset of dyspnoea and was diagnosed with mechanical valve thrombosis, which was managed with thrombolysis. However, the valve became stuck again just a week after the initial episode while the patient was still in the hospital and was receiving anticoagulation within the target range. Concurrently, he experienced skin rashes and itching, prompting an investigation that revealed hypereosinophilia secondary to parasite infestation. The patient's valve functions well after thrombolysis and parasite infection treatment. The eosinophil counts were monitored to remain within the normal range.

Indexed as

EosinophiliaHeart Valve ProsthesisMitral ValveThrombosisAnticoagulantsHeart Valve Prosthesis ImplantationHumansMaleMiddle AgedRecurrenceThrombolytic TherapyAnticoagulantsAllergyHaematology (incl blood transfusion)ThrombosisTropical medicine (infectious disease)Valvar diseases

Identifiers

PMID40588302
PMCPMC12210346

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.