Evidence map›Paper›PMID 40587506›Full record

ArticlePLOS digital health2025

Significant reduction in manual annotation costs in ultrasound medical image database construction through step by step artificial intelligence pre-annotation.

Fu Zheng, Liu XingMing, Xu JuYing, Tao MengYing, Yang BaoJian, Shan Yan, Ye KeWei, Lu ZhiKai, Huang Cheng, Qi KeLan and 6 more

Abstract read
In one paragraph

Article in PLOS digital health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Fu ZhengThe Ultrasound Diagnosis Department, The 906th Hospital of Joint Logistics Support Force of PLA, Ningbo City, Zhejiang Province, China.ORCID https://orcid.org/0000-0002-0609-2749
Liu XingMingThe Ultrasound Diagnosis Department, The 906th Hospital of Joint Logistics Support Force of PLA, Ningbo City, Zhejiang Province, China.
Xu JuYingThe Ultrasound Diagnosis Department, The 906th Hospital of Joint Logistics Support Force of PLA, Ningbo City, Zhejiang Province, China.
Tao MengYingThe Ultrasound Diagnosis Department, The 906th Hospital of Joint Logistics Support Force of PLA, Ningbo City, Zhejiang Province, China.
Yang BaoJianThe Ultrasound Diagnosis Department, The 906th Hospital of Joint Logistics Support Force of PLA, Ningbo City, Zhejiang Province, China.
Shan YanThe Ultrasound Diagnosis Department, The 906th Hospital of Joint Logistics Support Force of PLA, Ningbo City, Zhejiang Province, China.
Ye KeWeiThe Ultrasound Diagnosis Department, The 906th Hospital of Joint Logistics Support Force of PLA, Ningbo City, Zhejiang Province, China.
Lu ZhiKaiThe Ultrasound Diagnosis Department, The 906th Hospital of Joint Logistics Support Force of PLA, Ningbo City, Zhejiang Province, China.
Huang ChengThe Ultrasound Diagnosis Department, The 906th Hospital of Joint Logistics Support Force of PLA, Ningbo City, Zhejiang Province, China.
Qi KeLanThe Ultrasound Diagnosis Department, The 906th Hospital of Joint Logistics Support Force of PLA, Ningbo City, Zhejiang Province, China.
Chen XiHaoThe Ultrasound Diagnosis Department, The 906th Hospital of Joint Logistics Support Force of PLA, Ningbo City, Zhejiang Province, China.
Du WenFeiThe Ultrasound Diagnosis Department, The 906th Hospital of Joint Logistics Support Force of PLA, Ningbo City, Zhejiang Province, China.
He PingThe Ultrasound Diagnosis Department, The 906th Hospital of Joint Logistics Support Force of PLA, Ningbo City, Zhejiang Province, China.
Wang RunYuState Power Investment Corporation, Ningbo City, Zhejiang Province, China.
Ying YingThird Rehabilitation Zone, Hangzhou Rehabilitation Center for Special Duty Service Men of the PLA Air Force, Hangzhou City, Zhejiang Province, China.
Bu XiaoHuiThe Ultrasound Diagnosis Department, Hangzhou Special Service Sanatorium of the PLA Air Force, Hangzhou City, Zhejiang Province, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study investigates the feasibility of reducing manual image annotation costs in medical image database construction by utilizing a step by step approach where the Artificial Intelligence model (AI model) trained on a previous batch of data automatically pre-annotates the next batch of image data, taking ultrasound image of thyroid nodule annotation as an example. The study used YOLOv8 as the AI model. During the AI model training, in addition to conventional image augmentation techniques, augmentation methods specifically tailored for ultrasound images were employed to balance the quantity differences between thyroid nodule classes and enhance model training effectiveness. The study found that training the model with augmented data significantly outperformed training with raw images data. When the number of original images number was only 1,360, with 7 thyroid nodule classifications, pre-annotation using the AI model trained on augmented data could save at least 30% of the manual annotation workload for junior physicians. When the scale of original images number reached 6,800, the classification accuracy of the AI model trained on augmented data was very close with that of junior physicians, eliminating the need for manual preliminary annotation.

Identifiers

PMID40587506
PMCPMC12208487

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.