Evidence map›Paper›PMID 40587483›Full record

ArticlePloS one2025

Conformational eyelid disorders in dogs under primary veterinary care in the UK - Epidemiology and clinical management.

Dan G O'Neill, Minna P Mustikka, Dave C Brodbelt, David B Church, Vilma Vaattovaara

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Article in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Dan G O'NeillPathobiology and Population Sciences, The Royal Veterinary College, Hatfield, Herts, United Kingdom.ORCID 0000-0003-1115-2723
Minna P MustikkaDepartment of Equine and Small Animal Medicine, Faculty of Veterinary Medicine, University of Helsinki, Finland.ORCID 0000-0002-7180-1660
Dave C BrodbeltPathobiology and Population Sciences, The Royal Veterinary College, Hatfield, Herts, United Kingdom.
David B ChurchClinical Sciences and Services, The Royal Veterinary College, Hatfield, Herts, United Kingdom.
Vilma VaattovaaraPathobiology and Population Sciences, The Royal Veterinary College, Hatfield, Herts, United Kingdom.ORCID 0009-0006-1847-4281

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionNatural eyelid conformation is essential for normal function and health of the ocular surface. However, many modern dog types are deliberately bred for abnormal eyelid conformation associated with severe health and welfare issues. This study aimed to report the prevalence, demographic risk factors and clinical management under primary veterinary care for conformational eyelid disorders in dogs.

methodsThe study explored the anonymised clinical records of all dogs under UK primary veterinary care within the VetCompass Programme during 2019. Risk factor analysis used multivariable logistic regression modelling.

resultsFrom 2,250,417 dogs under primary veterinary care in 2019, the analysis included a random sample of 3,029 confirmed conformational eyelid disorder cases that included 2,752 (90.86%) entropion and 344 (11.36%) ectropion cases. After accounting for the subsampling process, the annual prevalence for overall conformational eyelid disorder in dogs was 0.36% (95% CI: 0.35-0.37). The annual prevalence for entropion in dogs overall was 0.33% (95% CI: 0.32-0.34). Breeds with highest annual prevalence for entropion were Shar-Pei (15.41%, 95% CI 14.00-16.91), Chow Chow (9.28%, 95% CI 7.64-11.14) and Neapolitan Mastiff (6.88%, 95% CI 3.02-13.14). The estimated annual prevalence for ectropion in dogs overall was 0.04% (95% CI: 0.04-0.05). Breeds with the highest annual prevalence for ectropion were Neapolitan Mastiff (4.30%, 95% CI 1.41-9.77), Saint Bernard (1.72%, 95% CI 0.86-3.05) and Basset Hound (1.59%, 95% CI 0.94-2.49). Surgical management was carried out for 414/2275 (18.20%) of the incident (2019) entropion cases and 12/305 (3.93%) of the incident (2019) ectropion cases.

conclusionsNormalisation of conformation-related health issues in certain high profile dog breeds have been discussed as a canine welfare priority for over half a century. The current results suggest that substantial work remains to be done to ensure good innate health for all dogs.

Indexed as

Dog DiseasesEctropionEntropionEyelid DiseasesAnimalsDogsEyelidsFemaleMalePrevalenceRisk FactorsUnited Kingdom

Identifiers

PMID40587483
PMCPMC12208470

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.