Evidence map›Paper›PMID 40587264›Full record

ReviewBiochemical Society transactions2025

Regulation of adipogenesis by nucleotides.

Julia A Pinette, Heather G Bryant, Jacob W Myers, Elma Zaganjor

Abstract readReview
In one paragraph

Review in Biochemical Society transactions, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Julia A PinetteDepartment of Molecular Physiology and Biophysics, Vanderbilt University School of Medicine, Nashville, TN, U.S.A.
Heather G BryantDepartment of Molecular Physiology and Biophysics, Vanderbilt University School of Medicine, Nashville, TN, U.S.A.ORCID 0009-0008-3086-6266
Jacob W MyersDepartment of Molecular Physiology and Biophysics, Vanderbilt University School of Medicine, Nashville, TN, U.S.A.ORCID 0000-0002-0288-2161
Elma ZaganjorDepartment of Molecular Physiology and Biophysics, Vanderbilt University School of Medicine, Nashville, TN, U.S.A.ORCID 0000-0003-0600-7417

Funding

Reprogramming cell fate through nucleotide metabolismR35GM154684 · NIGMS · VANDERBILT UNIVERSITY · PI Elma Zaganjor · 2024 to 2026
$1.2M
NIGMS NIH HHS R35 GM154684
6 · The paper itself

Abstract

The process by which multipotent cells commit to differentiate into distinct cell types, eventually forming functional tissues and organisms, has fascinated scientists for decades. Consequently, numerous studies have contributed to our understanding of how transcription factors and signaling molecules regulate differentiation. A growing area of interest in the field centers around the role of nutrients and metabolic pathways in cell fate determination. This review focuses on adipogenesis (also termed hyperplasia), the formation of adipocytes, which are key sensors of nutrient availability. We will examine recent findings that reshape our understanding of how nucleotide metabolism regulates adipogenesis.

Indexed as

AdipogenesisNucleotidesAdipocytesAnimalsCell DifferentiationHumansSignal TransductionNucleotidesadipogenesislipid metabolismmetabolic regulationmitochondriapurinergic signalingwhite adipose tissue

Identifiers

PMID40587264
PMCPMC12312395

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.