ArticleInterdisciplinary cardiovascular and thoracic surgery2025
The reduction of ectopic burden after mitral valve surgery in patients with mitral annular disjunction.
Article in Interdisciplinary cardiovascular and thoracic surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Mitral Valve Surgery with and Without Mitral Annular Disjunction: A Meta-Analysis.Journal of cardiovascular development and disease · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesMitral annular disjunction is a recognized risk factor for malignant ventricular arrhythmias in patients with mitral valve prolapse. This study aimed to evaluate the impact of mitral valve surgery on the burden of supraventricular and ventricular ectopic activity in patients with mitral annular disjunction.
methodsData from 32 patients who underwent mitral valve surgery between 2017 and 2024 were retrospectively analysed. The primary end-point was the change in the burden of supraventricular and ventricular ectopy following surgery. The secondary end-point was to assess whether this change differed according to the extent of the mitral annular disjunction distance.
resultsThe mean age of the patients was 38.8 ± 14 years, and 53.1% were female. The vast majority (96.9%) underwent successful mitral valve repair. The mean cardiopulmonary bypass and aortic cross-clamp times were 133.3 ± 38 min and 95.8 ± 32 min, respectively. Postoperatively, the mean burden of supraventricular ectopy decreased from 13.8% to 3.7%, and ventricular ectopy burden decreased from 7.1% to 2.1%. Among patients with a mitral annular disjunction distance ≥8.5 mm, both supraventricular and ventricular ectopic activity significantly declined. In contrast, for those with a mitral annular disjunction distance <8.5 mm, a significant reduction was observed only in ventricular ectopy, with no statistically significant change in supraventricular ectopy.
conclusionsMitral valve surgery is associated with a substantial reduction in both supraventricular and ventricular ectopic activity in patients with mitral annular disjunction. Furthermore, a mitral annular disjunction distance greater than 8.5 mm appears to be a predictor of a more pronounced reduction in arrhythmic burden following surgery.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.