Evidence map›Paper›PMID 40587045›Full record

ArticleJournal of fluorescence2025

Sustainable Fluorescence-off Based Analytical Approach for the Quantification of Linagliptin Using a Biocompatible Sensor; Erythrosine B Dye.

Ahmed Abdulhafez Hamad, Bassam Shaaban Mohammed, Abdelsalam Mohamed Abdelsalam Ouf, Ibrahim A Darwish, Abdulsalam Ashkar, Ahmed M Haredy

Abstract read
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In one paragraph

Article in Journal of fluorescence, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ahmed Abdulhafez HamadDepartment of Pharmaceutical Analytical Chemistry, Faculty of Pharmacy, Assiut Branch, Al-Azhar University, Assiut, 71524, Egypt. ahmedabdelhafez@azhar.edu.eg.
Bassam Shaaban MohammedDepartment of Pharmaceutical Analytical Chemistry, Faculty of Pharmacy, Menoufia University, Shebin El-Kom, Menoufia, 32511, Egypt.
Abdelsalam Mohamed Abdelsalam OufPharmaceutical Medicinal Chemistry& Drug Design Department, Faculty of Pharmacy, Al-Azhar University, Assiut, 71524, Egypt.
Ibrahim A DarwishDepartment of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, P.O. Box 2457, Riyadh, 11451, Saudi Arabia. idarwish@ksu.edu.sa.
Abdulsalam AshkarDepartment of Health Science, University of Eastern Piedmont, Via Solaroli, 17, Novara, 28100, Italy.
Ahmed M HaredyPharmaceutical Analytical Chemistry Department, Faculty of Pharmacy, Merit University, New Sohag, Egypt.

Funding

Ongoing Research Funding Program, (ORF-2025-944), King Saud University, Riyadh, Saudi Arabia. ORF-2025-944
6 · The paper itself

Abstract

A fluorescence quenching strategy was conceptualized to establish an environmentally compatible analytical system for trace-level detection of Linagliptin (LGP), an anti-diabetic pharmaceutical compound. This research delineates a biochemical sensing mechanism relying on an electrostatic coupling between LGP and Erythrosine B (EB), a biologically certified fluorophore, within optimized acidic parameters. The molecular association induced a concentration-dependent reduction in EB's intrinsic emission intensity at λ

Indexed as

Biocompatible MaterialsErythrosineFluorescent DyesLinagliptinFluorescenceSpectrometry, FluorescenceBiocompatible MaterialsErythrosineFluorescent DyesLinagliptinEcological impact evaluationElectrostatic biosensingFluorescence-quenching analytical platformSustainable detection using biocompatible EB dyeTrace-level LGP analysis

Identifiers

PMID40587045

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.