Holistic Approach to Investigate Pyrrolizidine Alkaloids in Honeys from Diverse Botanical Origin: From Target to Suspect and Nontarget Screening Analysis.

Laura Carbonell-Rozas, José Raúl Belmonte-Sánchez, Paula Soto-Rosiña, Roberto Romero-González, Antonia Garrido Frenich

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Article in Journal of agricultural and food chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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5 · Who and what money

Authors and funding

5 authors.

Laura Carbonell-RozasResearch Group "Analytical Chemistry of Contaminants", Department of Chemistry and Physics, Research Centre for Mediterranean Intensive Agrosystems and Agrifood Biotechnology (CIAIMBITAL), Agrifood Campus of International Excellence (ceiA3), University of Almeria, E-04120 Almeria, Spain.ORCID 0000-0002-2193-3737

José Raúl Belmonte-SánchezResearch Group "Analytical Chemistry of Contaminants", Department of Chemistry and Physics, Research Centre for Mediterranean Intensive Agrosystems and Agrifood Biotechnology (CIAIMBITAL), Agrifood Campus of International Excellence (ceiA3), University of Almeria, E-04120 Almeria, Spain.

Paula Soto-RosiñaResearch Group "Analytical Chemistry of Contaminants", Department of Chemistry and Physics, Research Centre for Mediterranean Intensive Agrosystems and Agrifood Biotechnology (CIAIMBITAL), Agrifood Campus of International Excellence (ceiA3), University of Almeria, E-04120 Almeria, Spain.

Roberto Romero-GonzálezResearch Group "Analytical Chemistry of Contaminants", Department of Chemistry and Physics, Research Centre for Mediterranean Intensive Agrosystems and Agrifood Biotechnology (CIAIMBITAL), Agrifood Campus of International Excellence (ceiA3), University of Almeria, E-04120 Almeria, Spain.ORCID 0000-0002-2505-2056

Antonia Garrido FrenichResearch Group "Analytical Chemistry of Contaminants", Department of Chemistry and Physics, Research Centre for Mediterranean Intensive Agrosystems and Agrifood Biotechnology (CIAIMBITAL), Agrifood Campus of International Excellence (ceiA3), University of Almeria, E-04120 Almeria, Spain.ORCID 0000-0002-7904-7842

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study investigates the presence of pyrrolizidine alkaloids (PAs) in honey from diverse botanical origins using a combination of target analysis, through ultrahigh-performance liquid chromatography coupled with tandem mass spectrometry and suspect and nontarget screening via ultrahigh-performance liquid chromatography coupled with quadrupole-Orbitrap high-resolution mass spectrometry. A total of 80 honey samples were analyzed, with 61% were found to contain at least one PA. Eucalyptus and wildflower honeys showed the highest contamination levels, reaching 27 μg/kg when expressed as the sum of regulated PAs. Indicine and lycopsamine, commonly associated with

Indexed as

Food ContaminationHoneyPyrrolizidine AlkaloidsChromatography, High Pressure LiquidEchiumEucalyptusMolecular StructureTandem Mass SpectrometryPyrrolizidine Alkaloidshoneymolecular networkingplant toxinspyrrolizidine alkaloidsscreening analysis

Identifiers

PMID40586875

DOI10.1021/acs.jafc.5c05585

PMCPMC12356582

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