ArticleOphthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists)2025
Three-year myopia management efficacy of extended depth of focus soft contact lenses (MYLO) in Caucasian children.
Article in Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Longitudinal changes in retinal image quality in school-aged children.Biomedical optics express · 2026Article
- Myopia management functional lenses (MMFL): a bibliometric analysis of multidisciplinary perspective and trend insights in the context of vision health.International ophthalmology · 2026Review
- Three-year myopia management efficacy of extended depth of focus soft contact lenses (MYLO) in Caucasian children.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2025Article
- Multifocal contact lenses and defocus incorporated multiple segments lenses slow myopic progression in Chinese children with high myopia.Journal of optometryArticle
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Authors and funding
5 authors.
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Abstract
purposeTo evaluate the progression of myopia as assessed by changes in axial length (AL) and spherical equivalent (SE) in Caucasian children wearing extended depth of focus soft contact lenses (CL) compared with distance single-vision spectacles after 3 years.
methodsA total of 96 progressing (at least -0.75 D increase in the previous 12 months) myopic children (aged 6-13 years) with SE ranging from -0.75 to -10.00 D were recruited. Forty-five children were fitted with CL (MYLO), whereas 51 wore spectacles. Cycloplegic refraction was measured with an auto-refractometer and AL with the Zeiss IOLMaster-700 at 6-month intervals. Subjective responses of CL wear were determined using a questionnaire on a scale of 1 (very poor) to 10 (excellent). High-contrast visual acuity (HCVA) was also evaluated.
resultsA total of 43 and 41 children achieved 3 years of wear with CL and spectacles, respectively. Mean change in SE and AL was -0.90 ± 0.36 D and 0.55 ± 0.04 mm in the CL group and -1.64 ± 0.26 D and 0.97 ± 0.03 mm in the spectacle group, respectively (all p < 0.001). The cumulative absolute reduction in axial elongation was 0.42 mm. The difference in SE change was 0.74 D. While 90% of the children wearing CL had an AL increase of ≤0.60 mm, 96% of the spectacle group increased by at least 0.91 mm. Indeed, 50% of the CL group showed myopia progression of at least 0.75 D, whereas all the spectacle group progressed by at least 0.75 D. Subjective responses indicated a mean value ≥9. There was a reduction in HCVA of half a logMAR line with CL compared to spectacles (p < 0.001).
conclusionsThree years of wear with MYLO CL resulted in clinically significant slower myopia progression compared to the SV spectacle group.
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