Evidence map›Paper›PMID 40586283›Full record

ArticleCancer research communications2025

Assessing Racial Disparities in Guideline-Concordant Care and Clinical Outcomes after Surgical Resection of Nonmetastatic Colon Cancer at a Comprehensive Cancer Center.

Christina I Lee, Sharafudeen D Abubakar, Fan Wu, Hannah M Thompson, Farheen Shah, Michele Waters, Jonathan B Yuval, Hannah Williams, Anisha Luthra, Dana M Omer and 3 more

Abstract read
In one paragraph

Article in Cancer research communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Exploring disparities in adherence to colorectal cancer clinical practice guidelines and associated survival outcomes: a systematic review and meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Christina I LeeDepartment of Surgery, Colorectal Service, Memorial Sloan Kettering Cancer Center, New York, New York.ORCID 0009-0009-7432-5733
Sharafudeen D AbubakarDepartment of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, New York.ORCID 0000-0002-2947-589X
Fan WuDepartment of Surgery, Colorectal Service, Memorial Sloan Kettering Cancer Center, New York, New York.ORCID 0000-0002-3960-320X
Hannah M ThompsonDepartment of Surgery, Colorectal Service, Memorial Sloan Kettering Cancer Center, New York, New York.ORCID 0000-0003-3405-5184
Farheen ShahDepartment of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, New York.ORCID 0009-0000-2194-6573
Michele WatersDepartment of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, New York.ORCID 0000-0002-5416-5172
Jonathan B YuvalDepartment of Surgery, Colorectal Service, Memorial Sloan Kettering Cancer Center, New York, New York.ORCID 0000-0002-9251-8303
Hannah WilliamsDepartment of Surgery, Colorectal Service, Memorial Sloan Kettering Cancer Center, New York, New York.ORCID 0000-0001-8928-4190
Anisha LuthraDepartment of Surgery, Colorectal Service, Memorial Sloan Kettering Cancer Center, New York, New York.ORCID 0000-0001-9007-3462
Dana M OmerDepartment of Surgery, Colorectal Service, Memorial Sloan Kettering Cancer Center, New York, New York.ORCID 0000-0002-2259-2540
Chin-Tung ChenDepartment of Surgery, Colorectal Service, Memorial Sloan Kettering Cancer Center, New York, New York.ORCID 0000-0002-3887-6070
Julio Garcia-AguilarDepartment of Surgery, Colorectal Service, Memorial Sloan Kettering Cancer Center, New York, New York.ORCID 0000-0003-2451-0948
Francisco Sanchez-VegaDepartment of Surgery, Colorectal Service, Memorial Sloan Kettering Cancer Center, New York, New York.ORCID 0000-0002-2990-4893

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI SELWYN M VICKERS · 1985 to 2026
$347.4M
NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

In this study, we examined racial disparities in guideline-concordant care (GCC) and clinical outcomes of patients with colon cancer treated at a single comprehensive cancer center. We analyzed data from self-reported Hispanic, non-Hispanic Black (NHB), and non-Hispanic White (NHW) patients who underwent curative colectomy for stage I to III colon cancer between 2006 and 2021 at Memorial Sloan Kettering Cancer Center. GCC was defined as retrieval of ≥12 lymph nodes and appropriate receipt of adjuvant chemotherapy. Recurrence and overall survival from the time of surgery were compared using the Kaplan-Meier method and the log-rank test. Multivariable analyses were performed using Cox regression. The study included 2,209 patients, with 1,911 NHW, 153 NHB, and 145 Hispanic patients. NHW patients were older, whereas NHB patients had higher percentages of Medicaid coverage, obesity, and lower socioeconomic status. NHB patients more often presented with stage III disease and underwent open surgery. Receipt of GCC was not different by race. NHB patients had the highest 5-year recurrence rate compared with NHW and Hispanic patients (27% vs. 15.7% vs. 15.1%; P = 0.03). NHB race (HR = 1.43; P = 0.07) and low body mass index (HR = 1.98; P = 0.05) were associated with an increased risk of recurrence with marginal significance. NHB race was associated with an increased risk of recurrence in stage I disease (HR = 3.52; P = 0.03). NHB patients had shorter recurrence-free survival, despite standardized quality of care. NHB race was independently associated with an increased risk of recurrence in stage I disease. SIGNIFICANCE: This study compares receipt of GCC, disease recurrence, and survival among White, Black, and Hispanic patients with nonmetastatic colon cancer treated at a single comprehensive cancer center with standardized quality of care and comparable access to health care. Black patients had higher rates of recurrence in this study.

Indexed as

ColectomyColonic NeoplasmsGuideline AdherenceHealthcare DisparitiesAdultAgedAged, 80 and overBlack or African AmericanCancer Care FacilitiesChemotherapy, AdjuvantFemaleHispanic or LatinoHumansMaleMiddle AgedNeoplasm Recurrence, Local

Identifiers

PMID40586283
PMCPMC12272046

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.