Evidence map›Paper›PMID 40586248›Full record

ArticlemBio2025

Cell wall remodeling in a fungal pathogen is required for hyphal growth into microspaces.

Hinata Miki, Melani Mariscal Gomez, Ayaka Itani, Daisuke Yamanaka, Yoshikatsu Sato, Antonio Di Pietro, Norio Takeshita

Abstract read
In one paragraph

Article in mBio, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Hinata Miki *Microbiology Research Center for Sustainability (MiCS), Faculty of Life and Environmental Sciences, Tsukuba Institute for Advanced Research (TIAR), University of Tsukuba, Tsukuba, Japan.
Melani Mariscal Gomez *Departamento de Genética, Campus de Excelencia Internacional Agroalimentario ceiA3, Universidad de Córdoba, Córdoba, Spain.ORCID 0000-0001-9179-1001
Ayaka ItaniMicrobiology Research Center for Sustainability (MiCS), Faculty of Life and Environmental Sciences, Tsukuba Institute for Advanced Research (TIAR), University of Tsukuba, Tsukuba, Japan.
Daisuke YamanakaLaboratory for Immunopharmacology of Microbial Products, School of Pharmacy, Tokyo University of Pharmacy and Life Sciences, Hachioji, Tokyo, Japan.
Yoshikatsu SatoInstitute of Transformative Bio-Molecules (WPI-ITbM), Nagoya University, Nagoya, Aichi, Japan.
Antonio Di PietroDepartamento de Genética, Campus de Excelencia Internacional Agroalimentario ceiA3, Universidad de Córdoba, Córdoba, Spain.ORCID 0000-0001-5930-5763
Norio TakeshitaMicrobiology Research Center for Sustainability (MiCS), Faculty of Life and Environmental Sciences, Tsukuba Institute for Advanced Research (TIAR), University of Tsukuba, Tsukuba, Japan.ORCID 0000-0003-2666-4991

Funding

Exploratory Research for Advanced Technology JPMJER1502Ministry of Education, Culture, Sports, Science and Technology 21H0209, 22H04878Ministry of Education, Culture, Sports, Science and Technology 23H04739, 24H01470Ministry of Education, Culture, Sports, Science and Technology 23K27411Noda Institute for Scientific ResearchOhsumi Frontier Science FoundationSpanish Ministry of Science and Innovation PID2022-140187OB-I00, PLEC2021-007777, TED2021-130262B-I00, PDC2022-133749-I00
6 · The paper itself

Abstract

Hyphae are filamentous structures that are crucial for the lifestyle of many fungi, allowing rapid colonization of diverse substrates such as dead organic material or living host tissue. One of the key features of fungal hyphae is their remarkable morphogenetic plasticity. During host colonization, phytopathogenic fungi must traverse extremely narrow spaces between plant cells such as the apoplastic space or the plasmodesmata. The mechanisms underlying hyphal plasticity during growth into microspaces are poorly understood. Here, we tested a set of isogenic mutants of

Indexed as

Cell WallFusariumHyphaeChitinFungal ProteinsGlucansMitogen-Activated Protein KinasesPlant DiseasesSolanum lycopersicumChitinFungal ProteinsGlucansMitogen-Activated Protein Kinasescell wallFusariumhyphaemicrofluidic devicemicrospacemitogen-activated protein kinasesplasticity

Identifiers

PMID40586248
PMCPMC12345142

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.