Evidence map›Paper›PMID 40585994›Full record

ArticleTheranostics2025

X-ray-responsive dissolving microneedles mediate STING pathway activation to potentiate cutaneous melanoma radio-immunotherapy.

Wen Hu, Xiaohong Hong, Xinyu Zhang, Hongfan Chen, Xin Wen, Feng Lin, Jingwen Liu, Chenfenglin Yang, Binglin Cheng, Hanrui Zhu and 4 more

Abstract read
In one paragraph

Article in Theranostics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Review
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  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Wen HuDepartment of Radiation Oncology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, China.
Xiaohong HongDepartment of Radiation Oncology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, China.
Xinyu ZhangState Key Laboratory of Bioactive Molecules and Druggability Assessment, Guangdong Basic Research Center of Excellence for Natural Bioactive Molecules and Discovery of Innovative Drugs, College of Pharmacy, Jinan University, Guangzhou, 511436, China.
Hongfan ChenDepartment of Radiation Oncology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, China.
Xin WenDepartment of Radiation Oncology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, China.
Feng LinDepartment of Radiation Oncology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, China.
Jingwen LiuSouthern Medical University, Guangzhou, 510515, China.
Chenfenglin YangDivision of Hepatobiliopancreatic Surgery, Department of General Surgery, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, China.
Binglin ChengDepartment of Radiation Oncology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, China.
Hanrui ZhuSouthern Medical University, Guangzhou, 510515, China.
Moting ZhangSouthern Medical University, Guangzhou, 510515, China.
Ruzhen ChenDepartment of Radiation Oncology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, China.
Tingting PengState Key Laboratory of Bioactive Molecules and Druggability Assessment, Guangdong Basic Research Center of Excellence for Natural Bioactive Molecules and Discovery of Innovative Drugs, College of Pharmacy, Jinan University, Guangzhou, 511436, China.
Xinran TangDepartment of Radiation Oncology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

ImmunotherapyMelanomaMelanoma, ExperimentalMembrane ProteinsSkin NeoplasmsAnimalsCell Line, TumorDrug Delivery SystemsHumansImmunogenic Cell DeathManganeseMiceMice, Inbred C57BLNanoparticlesNeedlesSignal TransductionManganeseMembrane ProteinsSting1 protein, mouseSTING Proteindissolving microneedlesmelanomaMn-ZIF-8radio-immunotherapyradiosensitization

Identifiers

PMID40585994
PMCPMC12203811

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.