ArticleJournal of surgical case reports2025
Long-term survival after extended resection combined with pericardiectomy for locally advanced intrahepatic cholangiocarcinoma: a case report.
Article in Journal of surgical case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
A 74-year-old man presented with upper gastrointestinal bleeding. Investigation revealed a locally advanced intrahepatic cholangiocarcinoma (ICC) arose from left liver invading duodenum and diaphragm. Left trisectionectomy combined with wedge duodenal resection, left diaphragmatic and pericardial resection was performed. The diaphragmatic/pericardial defect was closed with Gore-Tex mesh. The patient developed post-operative intra-abdominal collection which resolved with percutaneous drainage. Pathology confirmed a 7 cm ICC, there was evidence of rupture with abscess formation, and adhesion but no direct invasion to duodenum and diaphragm. The resection margin was clear. The patient remained well for over 2 years after surgery when he was noted to have a new 2.3 cm left lower lobe lung lesion. Biopsy of lesion showed mucinous adenocarcinoma, which could be lung primary or metastatic ICC. The lung tumor was successfully treated with stereotactic body radiotherapy. He remained well afterwards and survived for ˃5 years without further recurrence since initial operation.
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