Evidence map›Paper›PMID 40585890›Full record

ArticleTransplant international : official journal of the European Society for Organ Transplantation2025

Clinical and Histopathological Determinants for Kidney Allograft Survival in the Eurotransplant Senior Program (ESP) at the Time of Allocation.

Tom N Langer, Thorsten Wiech, Mercedes Noriega, Sergey Biniaminov, Tobias B Huber, Lutz Fischer, Florian Grahammer, Malte A Kluger

Abstract read
In one paragraph

Article in Transplant international : official journal of the European Society for Organ Transplantation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Tom N LangerIII. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Thorsten WiechInstitute of Pathology, Nephropathology Section, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Mercedes NoriegaInstitute of Pathology, Nephropathology Section, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Sergey BiniaminovHS Analysis GmbH, Karlsruhe, Germany.
Tobias B HuberIII. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Lutz FischerUniversity Transplant Center (UTC), University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Florian Grahammer *III. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Malte A Kluger *III. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To address the shortage of organs for kidney transplantation, the Eurotransplant Senior Program (ESP) was established to enhance kidney allocation from elderly donors. This study aimed to evaluate post-transplant outcomes of deceased donor grafts and identify prognostic factors within the ESP population. We therefore analyzed patient data from 64 ESP recipients and their donors transplanted at our center between 2017 and 2022. Time-zero biopsies were analyzed using AI image analysis software for glomerular density and glomerulosclerosis. One-year patient and allograft survival rates were 96.9% and 85.9%. 5-year survival rate was 74.6%, as opposed to about 41.0% historically reported for patients on dialysis. Delayed Graft Function occurred in 29.7% of cases, with recipient coronary heart disease, BMI-disparities, and prolonged cold ischemia time as major predictors (

Indexed as

Graft SurvivalKidney TransplantationTissue and Organ ProcurementAdultAgedAllograftsDelayed Graft FunctionFemaleHumansKidneyMaleMiddle AgedPrognosisRetrospective StudiesTissue DonorsAI histopathologyelderlyESP European Senior Programkidney transplantationmachine learning

Identifiers

PMID40585890
PMCPMC12203019

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.