ArticleBrain communications2025
Paramagnetic rim lesions in early multiple sclerosis: a 7 Tesla imaging study.
Article in Brain communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Smoldering neuroinflammation in progressive multiple sclerosis: mechanisms, imaging biomarkers, and therapeutic opportunities.Frontiers in immunology · 2026Review
- The Associations Between Chronic Active Lesions and White Matter Disease: A 7 Tesla Imaging Study.Annals of clinical and translational neurology · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
16 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Paramagnetic rim lesions (PRL) are considered biomarkers of chronic active lesions (CAL) in multiple sclerosis. The chronological relationship between CAL and disease severity in multiple sclerosis is not fully defined. In this cross-sectional, prospective study, we investigate the relationship between PRL and clinical/radiological measures of disease severity at the time of diagnosis of multiple sclerosis, clinically isolated syndrome, or radiologically isolated syndrome. Sixty-four treatment naïve people with newly diagnosed multiple sclerosis, clinically isolated syndrome, or radiologically isolated syndrome were consecutively enrolled. Each subject underwent 7.0 Tesla magnetic resonance imaging (MRI) and neurocognitive assessments. The MRI protocol included whole brain 3-dimensional acquisitions of: (i) magnetisation prepared 2 rapid gradient echoes, T
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.