Evidence map›Paper›PMID 40585767›Full record

ArticleExploration (Beijing, China)2025

Dual-Responsive Multi-Functional Silica Nanoparticles With Repaired Mitochondrial Functions for Efficient Alleviation of Spinal Cord Injury.

Guibin Gao, Juanjuan Li, Yanming Ma, Min Xie, Jianxian Luo, Ke Wang, Cheng Peng, Hua Yang, Tianjun Chen, Guowei Zhang and 3 more

Abstract read
In one paragraph

Article in Exploration (Beijing, China), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Guibin GaoDepartment of Dermatology, Guangdong Provincial Key Laboratory of Allergy & Immunology The Second Affiliated Hospital of Guangzhou Medical University Guangdong Key Laboratory of Urology and Department of Urology The First Affiliated Hospital of Guangzhou Medical University Guangzhou Guangzhou Institute of Cancer Research The Affiliated Cancer Hospital and School of Biomedical Engineering Guangzhou Medical University Guangdong China.
Juanjuan LiDepartment of Dermatology, Guangdong Provincial Key Laboratory of Allergy & Immunology The Second Affiliated Hospital of Guangzhou Medical University Guangdong Key Laboratory of Urology and Department of Urology The First Affiliated Hospital of Guangzhou Medical University Guangzhou Guangzhou Institute of Cancer Research The Affiliated Cancer Hospital and School of Biomedical Engineering Guangzhou Medical University Guangdong China.
Yanming MaHonghui Hospital Xi'an Jiaotong University Xi'an City China.
Min XieDepartment of Orthopedics The First Affiliated Hospital Jinan University Guangzhou Guangdong China.
Jianxian LuoDepartment of Orthopedics The First Affiliated Hospital Jinan University Guangzhou Guangdong China.
Ke WangDepartment of Orthopedics The First Affiliated Hospital Jinan University Guangzhou Guangdong China.
Cheng PengDepartment of Orthopedics The First Affiliated Hospital Jinan University Guangzhou Guangdong China.
Hua YangDepartment of Orthopedics The First Affiliated Hospital Jinan University Guangzhou Guangdong China.
Tianjun ChenDepartment of Orthopedics The First Affiliated Hospital Jinan University Guangzhou Guangdong China.
Guowei ZhangDepartment of Orthopedics The First Affiliated Hospital Jinan University Guangzhou Guangdong China.
Jiang OuyangDepartment of Dermatology, Guangdong Provincial Key Laboratory of Allergy & Immunology The Second Affiliated Hospital of Guangzhou Medical University Guangdong Key Laboratory of Urology and Department of Urology The First Affiliated Hospital of Guangzhou Medical University Guangzhou Guangzhou Institute of Cancer Research The Affiliated Cancer Hospital and School of Biomedical Engineering Guangzhou Medical University Guangdong China.ORCID https://orcid.org/0000-0003-3689-3237
Hongsheng LinDepartment of Orthopedics The First Affiliated Hospital Jinan University Guangzhou Guangdong China.ORCID https://orcid.org/0000-0002-6945-8875
Zhisheng JiDepartment of Orthopedics The First Affiliated Hospital Jinan University Guangzhou Guangdong China.ORCID https://orcid.org/0000-0002-0404-855X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Preserved/rescued mitochondrial functions have a significant effect on maintaining neurogenesis, axonal carriage, and synaptic plasticity following spinal cord injury (SCI). We fabricated an ingenious redox-responsive strategy for commanded liberation of NADH (reduced form of nicotinamide-adenine dinucleotide) by bioactive diselenide-containing biodegradable mesoporous silica nanoparticles (

Indexed as

diselenide‐containing mesoporous silica nanoparticlesmitochondrial functionsnanocarrierredox‐responsivespinal cord injury

Identifiers

PMID40585767
PMCPMC12199316

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.