Evidence map›Paper›PMID 40585744›Full record

ArticleCureus2025

From a Runny Nose to a Slow Heart: A Case Report About Disentangling the Mystery of A Heart Block Secondary to Influenza.

Sabavath Arun, Shivangi Sinha, Kundavaram Rajkumar, Amber Kumar, Shikha Malik

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sabavath ArunPediatrics, All India Institute of Medical Sciences, Bhopal, Bhopal, IND.
Shivangi SinhaPediatrics, All India Institute of Medical Sciences, Bhopal, Bhopal, IND.
Kundavaram RajkumarPediatrics, All India Institute of Medical Sciences, Raebareli, Raebareli, IND.
Amber KumarPediatrics, All India Institute of Medical Sciences, Bhopal, Bhopal, IND.
Shikha MalikPediatrics, All India Institute of Medical Sciences, Bhopal, Bhopal, IND.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Respiratory tract infections are frequently seen in children, with influenza responsible for the majority of hospital visits. While the respiratory manifestations of influenza are well recognized and managed by pediatricians, cardiovascular complications such as myocarditis, pericarditis, and conduction abnormalities are less commonly encountered and often overlooked. These complications, though rare, can have serious clinical implications if not promptly identified and treated. Here we present a rare case of influenza-induced third-degree heart block, which responded to dexamethasone therapy. A seven-month-old male child presented with fever, cough, rhinorrhea, and increased work of breathing. The child was initially managed as a case of pneumonia with intravenous antibiotics and supportive therapy. The findings from a chest radiograph were suggestive of viral pneumonia. With negative blood cultures and normal inflammatory markers, antibiotics were discontinued. Hemagglutinin Type 1 and Neuraminidase Type 1 (H1N1) influenza was confirmed on reverse transcription polymerase chain reaction (RT-PCR) testing. Though there was an improvement in the respiratory signs and symptoms, the child developed bradycardia with hypotension. Electrocardiography revealed a third-degree atrioventricular block with ST-T changes, normal cardiac structure, and preserved left ventricular function. Cardiac biomarkers were within normal limits. Despite the initiation of isoprenaline for persistent bradycardia, no improvement was seen. A short course of dexamethasone was administered, following which the child's cardiac rhythm reverted to the normal sinus rhythm. This case underscores the importance of considering cardiovascular complications, like conduction abnormalities, in children presenting with an influenza-like illness. Early recognition and timely corticosteroid therapy might restore normal cardiac conduction and potentially prevent the need for invasive interventions like the placement of a pacemaker.

Indexed as

atrioventricular heart blockatypical pneumoniadexamethasoneh1n1 influenzamyocarditis

Identifiers

PMID40585744
PMCPMC12206536

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.