Evidence map›Paper›PMID 40585734›Full record

ArticleCureus2025

Evaluating Ozonated Olive Oil and Chlorhexidine Gel as a Therapeutic Intervention for Periodontitis Stage II Grade A.

Maitri S Patel, Gaurav A Girdhar, Aseem Sharma, Prasanta Majumder, Anwesha Bhattacharjee, Mohd Shabankhan H Pathan, Shruti D Vyas, Mainul Haque, Santosh Kumar

Abstract read
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Maitri S PatelDepartment of Periodontology and Implantology, Karnavati School of Dentistry, Karnavati University, Gandhinagar, IND.
Gaurav A GirdharDepartment of Periodontology and Implantology, Karnavati School of Dentistry, Karnavati University, Gandhinagar, IND.
Aseem SharmaDepartment of Orthodontics and Dentofacial Orthopaedics, Himachal Institute of Dental Sciences, Paonta Sahib, IND.
Prasanta MajumderDepartment of Public Health Dentistry, Agartala Government Dental College and IGM Hospital, Agartala, IND.
Anwesha BhattacharjeeDepartment of Oral Medicine and Radiology, Agartala Government Dental College and IGM Hospital, Agartala, IND.
Mohd Shabankhan H PathanDepartment of Periodontology and Implantology, Karnavati School of Dentistry, Karnavati University, Gandhinagar, IND.
Shruti D VyasDepartment of Periodontology and Implantology, Karnavati School of Dentistry, Karnavati University, Gandhinagar, IND.
Mainul HaqueDepartment of Research, Karnavati School of Dentistry, Karnavati University, Gandhinagar, IND.
Santosh KumarDepartment of Periodontology and Implantology, Karnavati School of Dentistry, Karnavati University, Gandhinagar, IND.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction Periodontal therapy aims to eliminate harmful microorganisms from the gingival sulcus. Still, factors like deep pockets, tooth anatomy, and tissue-invading bacteria can reduce the effectiveness of scaling and root planing (SRP). Antimicrobial agents are often used to enhance SRP outcomes. While chlorhexidine (CHX) is commonly used, its limitations have prompted the exploration of alternatives like ozone therapy. Ozonated olive oil has shown potential therapeutic benefits. This study compares the effectiveness of CHX and ozonated olive oil as adjuncts to SRP in treating periodontitis stage II grade A. Materials and methods A longitudinal study with 20 participants was conducted. The control group received SRP with CHX, while the test group received SRP with ozonated olive oil. Clinical parameters, including probing depth, attachment loss, and sulcus bleeding index, were measured at baseline and after three months. Data were analyzed using the Student t-test. Results Both groups showed significant improvements in clinical parameters, with no significant differences. Conclusion Ozonated olive oil may enhance SRP outcomes in periodontal disease treatment and could be a valuable adjunct. Further studies are needed to confirm its long-term efficacy.

Indexed as

antimicrobial treatmentclinical parameterscomparative analysisgingival healthinflammatory responseoral microbiotaoxidative therapyperiodontal healingplaque controlpocket depth reduction

Identifiers

PMID40585734
PMCPMC12206067

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.