ArticleCureus2025
Smear- and Polymerase Chain Reaction (PCR)-Negative Tuberculosis: A Case Series Highlighting Diagnostic Limitations and the Role of Escalation.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
3 citing papers in PubMed.
- Serum tuberculosis biomarkers and their association with clinical characteristics among hospitalized adults living with HIV in Uganda.Journal of clinical tuberculosis and other mycobacterial diseases · 2026Article
- Paucibacillary Pleural Tuberculosis Presenting as Subpleural Nodules: A Diagnostic Challenge With Negative PCR and Smear Tests.Clinical case reports · 2026Article
- Article
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Tuberculosis (TB) remains a major global health concern, and its diagnosis can be particularly challenging when microbiological tests yield negative results. We present two diagnostically complex cases, one pulmonary and one pleural, in which tuberculosis was confirmed only after extended clinical evaluation and diagnostic escalation, resulting in delays of approximately eight weeks and two weeks, respectively. The first patient, a 31-year-old asymptomatic man with recent TB exposure, underwent bronchoalveolar lavage (BAL), with smear microscopy and polymerase chain reaction (PCR) both negative; cultures remained negative after eight weeks. He was later readmitted with hemoptysis, and repeat BAL ultimately yielded a positive culture for
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