Evidence map›Paper›PMID 40585578›Full record

ReviewRSC chemical biology2025

Advances in programmable DNA nanostructures enabling stimuli-responsive drug delivery and multimodal biosensing.

Yao Hong, Wenyue Ma, Meixia Wang, Hong-Hui Wang

Abstract readReview
In one paragraph

Review in RSC chemical biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yao HongState Key Laboratory of Chemo and Biosensing, College of Biology, Hunan Provincial Key Laboratory of Biomacromolecular Chemical Biology, Hunan University Changsha 410082 P. R. China wangmeixia@hnu.edu.cn wanghonghui@hnu.edu.cn.ORCID https://orcid.org/0009-0006-1670-8283
Wenyue MaState Key Laboratory of Chemo and Biosensing, College of Biology, Hunan Provincial Key Laboratory of Biomacromolecular Chemical Biology, Hunan University Changsha 410082 P. R. China wangmeixia@hnu.edu.cn wanghonghui@hnu.edu.cn.ORCID https://orcid.org/0009-0009-9308-7048
Meixia WangState Key Laboratory of Chemo and Biosensing, College of Biology, Hunan Provincial Key Laboratory of Biomacromolecular Chemical Biology, Hunan University Changsha 410082 P. R. China wangmeixia@hnu.edu.cn wanghonghui@hnu.edu.cn.ORCID https://orcid.org/0000-0002-9464-5293
Hong-Hui WangState Key Laboratory of Chemo and Biosensing, College of Biology, Hunan Provincial Key Laboratory of Biomacromolecular Chemical Biology, Hunan University Changsha 410082 P. R. China wangmeixia@hnu.edu.cn wanghonghui@hnu.edu.cn.ORCID https://orcid.org/0000-0002-4420-9733

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recent advancements in DNA nanotechnology have unlocked unprecedented opportunities to address critical challenges in precision medicine, particularly in targeted drug delivery and biomedical imaging. Conventional nanocarriers often suffer from poor spatiotemporal control, suboptimal tumor accumulation, and non-specific biodistribution. To overcome these limitations, DNA-engineered nanostructures-including tile-based assemblies, origami frameworks, spherical nucleic acids, and stimuli-responsive hydrogels-have emerged as programmable platforms capable of dynamically responding to tumor microenvironmental cues (

Identifiers

PMID40585578
PMCPMC12203123

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.