Evidence map›Paper›PMID 40585575›Full record

ReviewPatient preference and adherence2025

Effectiveness of Digital Health Interventions to Enhance Continuity of Care in Patients with Pulmonary Tuberculosis: A Systematic Review of Randomized Controlled Trials.

Qonita Nur Miladi, Tuti Pahria, Iqbal Pramukti

Abstract readReview
In one paragraph

Review in Patient preference and adherence, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Qonita Nur MiladiMaster Study Program, Faculty of Nursing, Universitas Padjadjaran, Sumedang, West Java, Indonesia.ORCID 0009-0002-2029-7860
Tuti PahriaDepartment of Medical-Surgical Nursing, Faculty of Nursing, Universitas Padjadjaran, Sumedang, West Java, Indonesia.
Iqbal PramuktiDepartment of Community Health Nursing, Faculty of Nursing, Universitas Padjadjaran, Sumedang, West Java, Indonesia.ORCID 0000-0002-0645-0534

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Pulmonary tuberculosis (TB) remains a global health concern with high morbidity and mortality rates. Despite being curable with proper treatment, challenges in ensuring continuity of care persist, particularly in resource-limited settings. Digital health interventions (DHI) offer a potential solution to improve treatment adherence and continuity of care among TB patients. Purpose: This study aimed to systematically review how DHIs contribute to improved continuity of care, particularly in terms of medication adherence, clinical outcomes, and patient satisfaction. Methods: A systematic review was conducted using PRISMA guidelines. Relevant studies were identified from five significant databases, including PubMed, Scopus, Taylor and Francis, EBSCO-host, and ScienceDirect, up to November 2024 and one search engine was Google Scholar. The keywords used were "pulmonary tuberculosis OR tbc OR tb AND mobile health applications OR mhealth OR mobile apps OR telehealth AND continuity of care OR patient compliance OR patient adherence OR adherence behaviour. Inclusion criteria focused on RCTs evaluating DHIs for adult TB patients. Data were extracted and analyzed thematically to assess intervention effectiveness on medication adherence and clinical outcomes. Results: A total of 17.380 patients from 21 studies TB patients were included. Interventions were classified into two categories: reminder-based (eg, SMS, phone calls, electronic medicine boxes with audio/visual alerts) and remote monitoring-based (eg, MERM, mobile applications, digital sensors, and VDOT). Compared to standard care, DHIs significantly improved medication adherence, treatment success rates, and patient satisfaction. Several studies also reported reduced time and cost burdens for patients. Conclusion: DHIs improve continuity of care among TB patients by increasing medication adherence and clinical outcomes. However, the effectiveness varies across different intervention types and settings, emphasizing the need for tailored strategies and integration into existing health systems.

Indexed as

adherencecontinuity of caredigital health interventionspulmonary tuberculosisrandomized controlled trials

Identifiers

PMID40585575
PMCPMC12204103

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.