Evidence map›Paper›PMID 40585478›Full record

SynthesisFrontiers in surgery2025

Risk of gastric cancer after bariatric surgery: a meta-analysis of retrospective studies.

Bing Li, Xiaoxuan Li, Jihong Peng, Pengfei Zhang

Abstract readSystematic Review
In one paragraph

Synthesis in Frontiers in surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Bing LiDepartment of General Surgery, Yiling Hospital of Yichang City, Yichang, Hubei, China.
Xiaoxuan LiDepartment of General Surgery, Yiling Hospital of Yichang City, Yichang, Hubei, China.
Jihong PengCollege of Basic Medical Sciences, China Three Gorges University, Yichang, Hubei, China.
Pengfei ZhangDepartment of General Surgery, Yiling Hospital of Yichang City, Yichang, Hubei, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: As obesity rates rise and Bariatric & Metabolic surgery (MBS) becomes more common, many patients with obesity opt for these procedures. Despite this, there are still concerns regarding the risk of postoperative gastric cancer. This study reviews comparative studies on the risk of gastric gancer among MBS vs. non MBS patients, reported in the last 15 years. Methods and study design: We conducted literature searches on PubMed, Web of Science, and Cochrane Library using specifically formulated terms and limited the publication period to 2000 to 2024. The number of people in the literature who underwent MBS and those who developed gastric cancer after MBS were extracted and statistically analyzed using RevMan 5.3. A random-effects model was employed to determine the merged odds ratio (OR) values, with the Mantel-Haenszel estimation method. Publication bias was assessed using a funnel plot. Heterogeneity between studies was analyzed with the Cochran Q (Chi-square) test and I² statistics. Results: A total of nine studies reported the incidence of gastric cancer, with a total of 1,025,852 patients with obesity in the MBS group and 7,171,376 patients with obesity in the matched control group. After excluding the confounding factors commonly associated with gastric cancer in the included studies, we found that the incidence rate of gastric cancer was comparable for parents after MBS and patients with obesity (OR = 0.98, 95% CI 0.50-1.94, Conclusions: It appears that there is no significant difference in the risk of gastric cancer between patients with obesity who have undergone MBS and those who have not, further investigation is needed to define the long term risk. Consequently, concerns can be reduced in patients with obesity who are in urgent need of MBS but are worried about developing gastric cancer. It provides evidence-based medicine evidence for clinical treatment.

Indexed as

bariatric and metabolic surgery MBSgastric cancermeta-analysisreviewsystermatic review

Identifiers

PMID40585478
PMCPMC12202535

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.