ArticleOxford medical case reports2025
Chronic leg ulcers in a patient with Hyperoxaluria type 1: a rare and challenging diagnosis.
Article in Oxford medical case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Calciphylaxis is an uncommon yet highly severe condition characterized by systemic medial calcification of arterioles, leading to ischemia and subsequent tissue necrosis. we report the case of a 29 year-old female suffering from primary hyperoxaluria type 1 and end-stage renal disease, Developed multiple painful ulcerations on her legs, initially believed to be due to cutaneous oxalosis. However, pathology findings revealed calciphylaxis. The association calciphylaxis and hyperoxaluria is rare, making this case unique. and she was treated with medical therapy, high-flow oxygen therapy and advanced wound dressings to facilitate granulation tissue formation and optimize ulcer healing, and daily hemodialysis with a low-calcium dialysate.
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