ArticleFrontiers in cardiovascular medicine2025
Association between the fibrosis-4 and the risk of left ventricular aneurysm formation in acute ST-segment elevation myocardial infarction.
Article in Frontiers in cardiovascular medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Fibrinogen-to-albumin ratio independently predicts left ventricular aneurysm in STEMI patients: a retrospective cohort study.Frontiers in cardiovascular medicine · 2026Article
- Elevated lactate dehydrogenase-to-albumin ratio: a novel and independent predictor of ventricular aneurysm in STEMI patients.Frontiers in endocrinology · 2026Article
- Monocyte-to-lymphocyte ratio as a predictor of left ventricular aneurysm in acute STEMI patients.Frontiers in endocrinology · 2025Article
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Authors and funding
3 authors.
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Abstract
Background: Left ventricular aneurysm (LVA) often occurs as a complication following an acute myocardial infarction. This research focused on assessing the ability of the fibrosis-4 (FIB-4) index to predict LVA formation in individuals with acute ST-segment elevation myocardial infarction (STEMI) who underwent primary percutaneous coronary intervention (PCI). Methods: We included 1,384 consecutive patients diagnosed with STEMI and compared their clinical and laboratory data between the LVA group and the non-LVA group. To determine the independent risk factors for LVA formation, multivariable logistic regression analysis was employed. Restricted cubic spline (RCS) analysis was conducted to evaluate the nonlinear relationship between FIB-4 index and LVA formation. The ROC curve was used to determine the predictive capability of the FIB-4 index and composite variable for LVA formation. Results: LVA occurred in 12.7% of the population. An elevated FIB-4 index correlated with a higher occurrence of LVA (19% vs. 9.3%, Conclusion: An increased FIB-4 index was positively associated with LVA formation in patients with acute STEMI who underwent primary PCI.
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