Evidence map›Paper›PMID 40585361›Full record

ArticleiScience2025

Angiotensin AT

Jhonatan Pasos, Valerie A Wagner, Samuel B R Lawton, Alyssa M Madison, Kush Nandani, Natalia M Mathieu, Connie C Grobe, John J Reho, Bonnie P Freudinger, Alexander J Sherman and 7 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in iScience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Jhonatan PasosDepartment of Physiology, Medical College of Wisconsin, Milwaukee, WI 53226, USA.
Valerie A WagnerDepartment of Physiology, Medical College of Wisconsin, Milwaukee, WI 53226, USA.
Samuel B R LawtonDepartment of Physiology, Medical College of Wisconsin, Milwaukee, WI 53226, USA.
Alyssa M MadisonDepartment of Physiology, Medical College of Wisconsin, Milwaukee, WI 53226, USA.
Kush NandaniDepartment of Physiology, Medical College of Wisconsin, Milwaukee, WI 53226, USA.
Natalia M MathieuDepartment of Physiology, Medical College of Wisconsin, Milwaukee, WI 53226, USA.
Connie C GrobeDepartment of Pediatrics, Division of Neonatology, Medical College of Wisconsin, Milwaukee, WI 53226, USA.
John J RehoDepartment of Physiology, Medical College of Wisconsin, Milwaukee, WI 53226, USA.
Bonnie P FreudingerEngineering Core, Medical College of Wisconsin, Milwaukee, WI 53226, USA.
Alexander J ShermanEngineering Core, Medical College of Wisconsin, Milwaukee, WI 53226, USA.
Daniel T BrozoskiDepartment of Physiology, Medical College of Wisconsin, Milwaukee, WI 53226, USA.
Lisa L MorselliDepartment of Medicine / Division of Endocrinology and Molecular Medicine, Medical College of Wisconsin, Milwaukee, WI 53226, USA.
Colin M L BurnettCardiovascular Center, Medical College of Wisconsin, Milwaukee, WI 53226, USA.
Jeffrey L SegarDepartment of Physiology, Medical College of Wisconsin, Milwaukee, WI 53226, USA.
Pablo NakagawaDepartment of Physiology, Medical College of Wisconsin, Milwaukee, WI 53226, USA.
Curt D SigmundDepartment of Physiology, Medical College of Wisconsin, Milwaukee, WI 53226, USA.
Justin L GrobeDepartment of Physiology, Medical College of Wisconsin, Milwaukee, WI 53226, USA.

Funding

Clinical and Translational Science AwardUL1TR001436 · NCATS · MEDICAL COLLEGE OF WISCONSIN · PI FREED, JULIE K · 2015 to 2025
$47.5M
Role of the brain Renin-Angiotensin Sys. in Cardiovas and Metabolic RegulationP01HL084207 · NHLBI · UNIVERSITY OF IOWA · PI GROBE, JUSTIN L · 2007 to 2022
$30.2M
TRANSGENIC COREP60DK020595 · NIDDK · UNIVERSITY OF CHICAGO · PI BELL, GRAEME I · 1985 to 2012
$25.5M
Pilot and Feasibility ProgramP30DK020595 · NIDDK · UNIVERSITY OF CHICAGO · PI RONALD N COHEN · 2013 to 2026
$20.9M
Medical Scientist Training ProgramT32GM080202 · NIGMS · MEDICAL COLLEGE OF WISCONSIN · PI BARBIERI, JOSEPH T, SALZMAN, NITA H · 2010 to 2024
$5.7M
PPARG-dependent Mechanisms Control Endothelial-Smooth Muscle Coordination, Arterial Pressure, Vasomotor Function and Arterial StiffnessR35HL144807 · NHLBI · MEDICAL COLLEGE OF WISCONSIN · PI SIGMUND, CURT DANIEL · 2019 to 2024
$5.5M
Interaction between leptin and angiotensin in the pathogenesis of obesity-hypertensionR01HL134850 · NHLBI · UNIVERSITY OF IOWA · PI Justin L Grobe · 2017 to 2026
$4.4M
Intersection of the PPARγ-RhoBTB1-Cullin-3 Pathway and Renin-Angiotensin System in Blood Pressure, Vascular Function and Arterial StiffnessR35HL177123 · NHLBI · MEDICAL COLLEGE OF WISCONSIN · PI Curt Daniel Sigmund · 2025 to 2026
$2.2M
Impact of Early Life Sodium Intake on Growth and Metabolism – Role of Hypothalamic MechanismsR01DK133121 · NIDDK · MEDICAL COLLEGE OF WISCONSIN · PI GROBE, JUSTIN L, SEGAR, JEFFREY L · 2022 to 2025
$1.9M
Advancing Student Potential for Inclusion with Research Experiences (ASPIRE)R25HL168782 · NHLBI · MEDICAL COLLEGE OF WISCONSIN · PI Joy Lincoln, Malika L Siker · 2023 to 2026
$662k
Role of the prorenin receptor in blood pressure and autonomic control through the local activation of the renin angiotensin system in the brainstemK01HL153101 · NHLBI · MEDICAL COLLEGE OF WISCONSIN · PI NAKAGAWA, PABLO · 2020 to 2024
$562k
3D PrinterS10OD032136 · OD · MEDICAL COLLEGE OF WISCONSIN · PI TEFFT, BRANDON J · 2022 to 2022
$77k
NCATS NIH HHS UL1 TR001436NHLBI NIH HHS K01 HL153101NHLBI NIH HHS P01 HL084207NHLBI NIH HHS R01 HL134850NHLBI NIH HHS R25 HL168782NHLBI NIH HHS R35 HL144807NHLBI NIH HHS R35 HL177123NIDDK NIH HHS P30 DK020595NIDDK NIH HHS P60 DK020595NIDDK NIH HHS R01 DK133121NIGMS NIH HHS T32 GM080202NIH HHS S10 OD032136
6 · The paper itself

Abstract

Subtypes of agouti-related peptide (AgRP) neurons can be distinguished based upon expression of angiotensin II receptors. The type 1 subtype, which expresses the angiotensin type 1 receptor (

Indexed as

Molecular biologyNeuroscienceOmics

Identifiers

PMID40585361
PMCPMC12205624

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.