Evidence map›Paper›PMID 40585340›Full record

ArticleAmerican journal of preventive cardiology2025

Factors and outcomes associated with adherence to statins among patients with newly diagnosed cardiovascular disease.

Jiang Li, Satish Mudiganti, Hannah Husby, J B Jones, Xiaowei Yan

Abstract read
In one paragraph

Article in American journal of preventive cardiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jiang LiSutter Health Center for Health Systems Research-West/Palo Alto Medical Foundation Research Institute, 795 El Camino Real, Ames Building, Palo Alto, CA 94301, USA.
Satish MudigantiSutter Health Center for Health Systems Research East, 2121 North California Blvd, Suite 310, Walnut Creek, CA, 94596, USA.
Hannah HusbySutter Health Center for Health Systems Research East, 2121 North California Blvd, Suite 310, Walnut Creek, CA, 94596, USA.
J B JonesSutter Health Center for Health Systems Research East, 2121 North California Blvd, Suite 310, Walnut Creek, CA, 94596, USA.
Xiaowei YanSutter Health Center for Health Systems Research East, 2121 North California Blvd, Suite 310, Walnut Creek, CA, 94596, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Statin use is proven to be effective in lowering low-density lipoprotein cholesterol (LDL-C) levels and reducing risk of recurrent myocardial infarction, stroke, and mortality in individuals with established cardiovascular disease (CVD). We used medication dispensed data (e.g., SureScripts), which has been integrated with the electronic health record (EHR) to examine the factors and outcomes associated with adherence to statins. Methods: This study is a secondary data analysis using longitudinal data between 1/1/2010-10/31/2021 ( Results: Of the 5155 patients with newly prescribed statins, a total of 3553 (68.9 %) were adherent, with insurance type, online patient portal use, race, age, statin intensity, and cardiologist visits emerging as significant predictors. Specifically, patients with PPO/FFS were less likely to fill statin prescriptions compared to those with HMO. Infrequent online patient portal use is associated with lower adherence. There is a disparity between patients race categories (Non-Hispanic Black (NHB) vs. Non-Hispanic White (NHW)) in filling the prescription and adhering to the filled prescription. Medication adherence is defined as proportion of days covered (PDC) of 80 % or greater. Adherence was positively associated with older age, high-intensity statins, and cardiologist visits. Having a visit with a cardiologist showed better adherence to the prescription and lowering of LDL values. Additionally, adhering to statins has shown a better outcome of lowering patients LDL values. Conclusions: The findings emphasize demographic and healthcare factors in medication adherence and LDL control, suggesting tailored interventions for diverse populations, addressing disparities in insurance type, race, and online portal use, and involving cardiologists in medication management for improved medication adherence and clinical outcomes.

Indexed as

Cardiovascular diseaseMedication adherenceStatins

Identifiers

PMID40585340
PMCPMC12206012

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.