Evidence map›Paper›PMID 40585337›Full record

ArticleAmerican journal of preventive cardiology2025

Association of life's essential 8 score with incidence of atrial fibrillation: The Framingham heart study.

Camilo Toro, Ayelet Shapira Daniels, Brenton Prescott, Vanessa Xanthakis, Matthew Nayor, Priya Gajjar, Emelia J Benjamin, Sarah R Preis

Abstract read
In one paragraph

Article in American journal of preventive cardiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Camilo ToroDepartment of Medicine, Boston University Chobanian and Avedisian School of Medicine, Boston, MA, USA.
Ayelet Shapira DanielsDepartment of Medicine, Boston University Chobanian and Avedisian School of Medicine, Boston, MA, USA.
Brenton PrescottSection of Preventive Medicine and Epidemiology, Boston University Chobanian and Avedisian School of Medicine, Boston, MA, USA.
Vanessa XanthakisDepartment of Medicine, Boston University Chobanian and Avedisian School of Medicine, Boston, MA, USA.
Matthew NayorNHLBI's Framingham Study, Framingham, MA, USA.
Priya GajjarSection of Cardiovascular Medicine, Boston Medical Center, Boston University Chobanian and Avedisian School of Medicine, Boston, MA, USA.
Emelia J BenjaminDepartment of Epidemiology, Boston University School of Public Health, Boston, MA, USA.
Sarah R PreisDepartment of Biostatistics, Boston University School of Public Health, Boston, MA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Atrial fibrillation (AF) burden can be reduced by targeting modifiable risk factors. Limited data exist on the association between American Heart Association's Life's Essential 8 (LE8) score (higher scores healthier) and AF incidence. Methods: We studied AF-free Framingham Heart Study Offspring and Omni 1 participants aged ≥45 years who attended ≥1 index exam in which LE8 components were assessed. LE8 scores were calculated incorporating body mass index, blood pressure, non-HDL cholesterol, glucose, smoking, physical activity, diet, and sleep. Fine-Gray hazards models, accounting for the competing risk of death, were used to calculate subdistribution hazards ratios (sHR) for the association of LE8 score and its components with 10-year AF incidence. Results: We included 3161 unique participants ( Conclusions: Lower LE8 scores were associated with greater risk of developing AF. Future studies of the role of LE8 in reducing AF burden in the overall population are warranted.

Indexed as

Atrial fibrillationLife's Essential 8

Identifiers

PMID40585337
PMCPMC12205587

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.