ArticleAsia Oceania journal of nuclear medicine & biology2025
A Prospective cohort study investigates the health consequences and biomarkers in Iraqi radiation workers.
Article in Asia Oceania journal of nuclear medicine & biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objectives: Objectives: Ionizing radiation has the potential to change the pattern of DNA methylation and can cause oxidative damage that may impact DNA. In this prospective cohort study, the effect of ionizing radiation on Iraqi radiation workers has been estimated by investigating the malondialdehyde levels, DNA methylation, DNA fragmentation, as well as the karyorrhectic, differentiated, and basal cells in buccal tissue. Methods: This work involved 80 participants, 40 hospital X-ray workers, and 40 control. Blood samples have been investigated using the NWLSS™ malondialdehyde assay, the gSYNC™ DNA extraction kit, and the comet assay. Results: The mean values of malondialdehyde level, DNA methylation, and DNA fragmentation (%DNA in tai), in workers were found to be 3.00±0.53, 51.63±26.44, and 26.73±12.67, respectively, while in the control were found to be 0.67±0.11, 13.25±11.30, and 9.09±11.96, respectively. In buccal tissue, the mean values of karyorrhectic cells, differentiated cells, late differentiated cells, and early differentiated cells in workers were found to be 7.70±4.64, 8.98±5.44, 14.74±5.25, and 18.50±6.40, respectively, while in control group were found to be 0.15±0.43, 0.20±0.41, 3.45±1.30, 10.78±1.80, respectively. The level of basal cells in buccal tissue was lower in workers (49.33±18.77) compared to the control group (85.75±2.19). Conclusions: The observed levels of biomarkers in radiation workers suggest adverse health consequences due to their occupational exposure to ionizing radiation. Controlling the exposure of hospital workers is the first step to improving the health of workers, thus decreasing economic and human costs.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.