Evidence map›Paper›PMID 40585256›Full record

ArticleResearch square2025

Multiplexed Targeted Spatial Mass Spectrometry Imaging Assays to monitor lipids and NAD

Birgit Schilling, Charles Schurman, Joanna Bons, Prasanna Kumaar, Jingji Fang, Andrea Roberts, Genesis Hormazabal, Rebeccah Riley, Nannan Tao, Eric Verdin

Abstract readPreprint
In one paragraph

Article in Research square, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Birgit SchillingBuck Institute for Research on Aging.ORCID 0000-0001-9907-2749
Charles SchurmanUniversity of California, San Francisco.ORCID 0000-0002-5739-8481
Joanna BonsBuck Institute for Research on Aging.ORCID 0000-0002-1110-4193
Prasanna KumaarBuck Institute for Research on Aging.
Jingji FangBuck Institute for Research on Aging.
Andrea RobertsBuck Institute for Research on Aging.
Genesis HormazabalBuck Institute for Research on Aging.
Rebeccah RileyBuck Institute Research on Aging.ORCID 0000-0002-5870-6837
Nannan TaoBruker.
Eric VerdinBuck Institute for Research on Aging.ORCID 0000-0003-3703-3183

Funding

Single cell analysis coreP01AG066591 · NIA · BUCK INSTITUTE FOR RESEARCH ON AGING · PI MELOV, SIMON · 2021 to 2025
$15.5M
Training in Basic Research on Aging and Age-Related DiseaseT32AG000266 · NIA · UNIVERSITY OF CALIF-LAWRENC BERKELEY LAB · PI Lisa M Ellerby · 1998 to 2026
$13.8M
Spatial Proteomics of osteoarthritis in bones to uncover disease progressionR21AR084303 · NIAMS · BUCK INSTITUTE FOR RESEARCH ON AGING · PI ALLISTON, TAMARA N, ANGEL, PEGGI M · 2024 to 2024
$457k
NIAMS NIH HHS R21 AR084303NIA NIH HHS P01 AG066591NIA NIH HHS T32 AG000266
6 · The paper itself

Abstract

Mass spectrometry imaging (MSI) is a rapidly advancing technology that provides mapping of the spatial molecular landscape of tissues for a variety of analytes. Matrix-assisted laser desorption/ionization (MALDI)-MSI is commonly employed, however, confident

Identifiers

PMID40585256
PMCPMC12204368

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.