Evidence map›Paper›PMID 40585242›Full record

ArticleResearch square2025

An induced pluripotent stem cell model of Schwann cell differentiation reveals NF2- related gene regulatory networks.

Olivia Lazaro, Sihong Li, William Carter, Jake Smiley, Oluwamayowa Awosika, Sylvia Robertson, Angela Haskell, Raven Hinkel, Brooke E Hickey, Steven P Angus and 5 more

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in Research square, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Olivia LazaroIndiana Biosciences Research Institute.
Sihong LiIndiana Biosciences Research Institute.
William CarterIndiana Biosciences Research Institute.
Jake SmileyIndiana Biosciences Research Institute.
Oluwamayowa AwosikaIndiana Biosciences Research Institute.
Sylvia RobertsonIndiana Biosciences Research Institute.
Angela HaskellIndiana Biosciences Research Institute.
Raven HinkelIndiana Biosciences Research Institute.
Brooke E HickeyIndiana University School of Medicine.
Steven P AngusIndiana University School of Medicine.
Austin HouseIndiana Biosciences Research Institute.
D Wade ClappIndiana University School of Medicine.
Abdul Q SyedIndiana Biosciences Research Institute.
Travis S JohnsonIndiana Biosciences Research Institute.
Steven D RhodesIndiana University School of Medicine.

Funding

Tumor Microenvironment and Metastasis ProgramP30CA082709 · NCI · INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS · PI David W Clapp · 1999 to 2026
$59.3M
A deep-transfer-learning framework to transfer clinical information to single cells and spatial locations in cancer tissuesR21CA264339 · NCI · INDIANA UNIVERSITY INDIANAPOLIS · PI JOHNSON, TRAVIS STEELE, ZHANG, JIE · 2022 to 2023
$394k
NCI NIH HHS P30 CA082709NCI NIH HHS R21 CA264339
6 · The paper itself

Abstract

Schwann cells are vital to development and maintenance of the peripheral nervous system and their dysfunction has been implicated in a range of neurological and neoplastic disorders, including

Indexed as

gene co-expression analysishiPSCNF2SchwannomascRNA-seqsystems biology

Identifiers

PMID40585242
PMCPMC12204348

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.